Gene detail

ITJ05_RS08540

Histidine kinase, Classic

Clostridioides difficile · GCF_015352255

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015352255#ITJ05_RS08540Stable P2CS identifier used across views.
GenomeGCF_015352255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747751Run 6 · 306 sequences · id 100% · cov 80%
External referencesWP_003420354.1 · D5Q6Z1 · MIST4 ITJ05_RS08540RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 467 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for ITJ05_RS08540
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.0000201:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000228:312:68:64
3 HATPase_c#3
359-464 aa · 106 aa · 22.7% of protein
Raw tokenHATPase_c:359:8.85e-25:464:107:109
  • Raw architecture: HAMP:166:0.0000201:232:69:69#HisKA:245:0.0000000000000228:312:68:64#HATPase_c:359:8.85e-25:464:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015352255::NZ_JADKQU010000018.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3324-5456Genomic interval covered by the local TCS group.
Identifiers
Old locus tagITJ05_08545RefSeq proteinWP_003420354.1
Context group IDGCF_015352255::NZ_JADKQU010000018.1::G00005
Context members
ITJ05_RS08535ITJ05_RS08540
Partner locus tags
ITJ05_RS08535ITJ05_RS08540
Partner old locus tags
ITJ05_08540ITJ05_08545
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003420354.1Primary protein accession used for annex mappings.
UniProt accessionD5Q6Z1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q6Z1_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagITJ05_RS08540Primary locus identifier stored in the genes table.
Old locus tagITJ05_08545Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JADKQU010000018.1Sequence record reported by the local genomic context database.
Genomic interval4 053-5 456 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 324-5 456 ntGCF_015352255::NZ_JADKQU010000018.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015352255::NZ_JADKQU010000018.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADKQU010000018.1All displayed genes belong to this local TCS context.
Neighborhood span3 324-5 456 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 324 nt5 456 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ITJ05_RS08535GCF_015352255#ITJ05_RS08535
RROmpR

3 324-4 049 nt · Forward (+)

Old locus ITJ05_08540RefSeq WP_003420352.1
ITJ05_RS08540GCF_015352255#ITJ05_RS08540
HKClassicCurrent focus

4 053-5 456 nt · Forward (+)

Old locus ITJ05_08545RefSeq WP_003420354.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747751Run 6 · HK · 306 sequences
Representative sequenceGCF_000155065#QAE_RS0208280Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747751

Simplified PFAM architecture for HKOC_1747751

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747751
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0208280

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015352255
AssemblyASM1535225v1 · Scaffoldhaploid
Genome composition3 912 632 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 95 · HK 48 · RR 47CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key