Gene detail

ITJ07_RS02750

Histidine kinase, Hybrid

Clostridioides difficile · GCF_015352055

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015352055#ITJ07_RS02750Stable P2CS identifier used across views.
GenomeGCF_015352055Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0484793Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_021370061.1 · MIST4 ITJ07_RS02750RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for ITJ07_RS02750
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:4.53e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.26e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:3.18e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:5.63e-27:848:118:111
  • Raw architecture: HisKA:344:4.53e-18:410:67:64#HATPase_c:458:5.26e-25:576:120:109#Response_reg:592:3.18e-22:696:105:111#Response_reg:731:5.63e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015352055::NZ_JADKQL030000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span537037-541605Genomic interval covered by the local TCS group.
Identifiers
Old locus tagITJ07_0002750RefSeq proteinWP_021370061.1
Context group IDGCF_015352055::NZ_JADKQL030000001.1::G00003
Context members
ITJ07_RS02750ITJ07_RS02760
Partner locus tags
ITJ07_RS02750ITJ07_RS02760
Partner old locus tags
ITJ07_0002750ITJ07_0002760
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021370061.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagITJ07_RS02750Primary locus identifier stored in the genes table.
Old locus tagITJ07_0002750Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JADKQL030000001.1Sequence record reported by the local genomic context database.
Genomic interval537 037-539 595 nt2 559 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span537 037-541 605 ntGCF_015352055::NZ_JADKQL030000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015352055::NZ_JADKQL030000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADKQL030000001.1All displayed genes belong to this local TCS context.
Neighborhood span537 037-541 605 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
537 037 nt541 605 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ITJ07_RS02750GCF_015352055#ITJ07_RS02750
HKHybridCurrent focus

537 037-539 595 nt · Reverse (-)

Old locus ITJ07_0002750RefSeq WP_021370061.1
ITJ07_RS02760GCF_015352055#ITJ07_RS02760
RRRpfG

539 965-541 605 nt · Reverse (-)

Old locus ITJ07_0002760RefSeq WP_009901919.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484793Run 6 · HK · 33 sequences
Representative sequenceGCF_000449025#QCG_RS02785Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484793

Simplified PFAM architecture for HKOC_0484793

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0484793
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449025#QCG_RS02785

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015352055
AssemblyASM1535205v3 · Scaffoldhaploid
Genome composition4 268 059 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key