Gene detail

ITJ06_RS02770

Histidine kinase, Classic

Clostridioides difficile · GCF_015351925

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_015351925#ITJ06_RS02770Stable P2CS identifier used across views.
GenomeGCF_015351925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737534Run 6 · 343 sequences · id 100% · cov 80%
External referencesWP_009892732.1 · A0A0H3MZP2 · MIST4 ITJ06_RS02770RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
HisKA: 245-309 aa (65 aa)1HATPase_c: 357-466 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.0000000000019:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:1.68e-17:466:111:109
  • Raw architecture: HisKA:245:0.0000000000019:309:65:64#HATPase_c:357:1.68e-17:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_015351925::NZ_JADKQC010000004.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span112523-114681Genomic interval covered by the local TCS group.
Identifiers
Old locus tagITJ06_02765RefSeq proteinWP_009892732.1
Context group IDGCF_015351925::NZ_JADKQC010000004.1::G00045
Context members
ITJ06_RS02770ITJ06_RS02775
Partner locus tags
ITJ06_RS02770ITJ06_RS02775
Partner old locus tags
ITJ06_02765ITJ06_02770
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892732.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZP2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZP2_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagITJ06_RS02770Primary locus identifier stored in the genes table.
Old locus tagITJ06_02765Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JADKQC010000004.1Sequence record reported by the local genomic context database.
Genomic interval112 523-113 929 nt1 407 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span112 523-114 681 ntGCF_015351925::NZ_JADKQC010000004.1::G00045

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_015351925::NZ_JADKQC010000004.1::G00045

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JADKQC010000004.1All displayed genes belong to this local TCS context.
Neighborhood span112 523-114 681 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
112 523 nt114 681 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ITJ06_RS02770GCF_015351925#ITJ06_RS02770
HKClassicCurrent focus

112 523-113 929 nt · Reverse (-)

Old locus ITJ06_02765RefSeq WP_009892732.1
ITJ06_RS02775GCF_015351925#ITJ06_RS02775
RROmpR

113 974-114 681 nt · Reverse (-)

Old locus ITJ06_02770RefSeq WP_009888460.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737534Run 6 · HK · 343 sequences
Representative sequenceGCF_000003215#QAC_RS0203465Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737534

Simplified PFAM architecture for HKOC_1737534

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737534
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0203465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_015351925
AssemblyASM1535192v1 · Scaffoldhaploid
Genome composition4 103 471 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key