Gene detail

H8S76_RS04190

Histidine kinase, Classic

Blautia celeris · GCF_014287615

ClassHKTypeClassicLength615 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_014287615#H8S76_RS04190Stable P2CS identifier used across views.
GenomeGCF_014287615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0989299Run 6 · 14 sequences · id 100% · cov 80%
External referencesWP_103730934.1 · A0ABR7F8D3 · MIST4 H8S76_RS04190RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length615 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage368 / 615 aa (59.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa615 aa
dCache_1: 187-297 aa (111 aa)1HAMP: 314-383 aa (70 aa)2His_kinase: 401-474 aa (74 aa)3HATPase_c: 496-608 aa (113 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
187-297 aa · 111 aa · 18.0% of protein
Raw tokendCache_1:187:0.0000347:297:114:195
2 HAMP#2
314-383 aa · 70 aa · 11.4% of protein
Raw tokenHAMP:314:0.000000000644:383:70:69
3 His_kinase#3
401-474 aa · 74 aa · 12.0% of protein
Raw tokenHis_kinase:401:2.22e-24:474:74:80
4 HATPase_c#4
496-608 aa · 113 aa · 18.4% of protein
Raw tokenHATPase_c:496:0.000000000000933:608:113:109
  • Raw architecture: dCache_1:187:0.0000347:297:114:195#HAMP:314:0.000000000644:383:70:69#His_kinase:401:2.22e-24:474:74:80#HATPase_c:496:0.000000000000933:608:113:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_014287615::NZ_JACOOU010000001.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span953628-957079Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8S76_04190RefSeq proteinWP_103730934.1
Context group IDGCF_014287615::NZ_JACOOU010000001.1::G00028
Context members
H8S76_RS04185H8S76_RS04190
Partner locus tags
H8S76_RS04185H8S76_RS04190
Partner old locus tags
H8S76_04185H8S76_04190
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_103730934.1Primary protein accession used for annex mappings.
UniProt accessionA0ABR7F8D3Primary UniProt accession resolved in the annex database.
UniProt IDA0ABR7F8D3_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8S76_RS04190Primary locus identifier stored in the genes table.
Old locus tagH8S76_04190Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOOU010000001.1Sequence record reported by the local genomic context database.
Genomic interval955 232-957 079 nt1 848 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span953 628-957 079 ntGCF_014287615::NZ_JACOOU010000001.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014287615::NZ_JACOOU010000001.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOOU010000001.1All displayed genes belong to this local TCS context.
Neighborhood span953 628-957 079 nt3 452 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
953 628 nt957 079 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H8S76_RS04185GCF_014287615#H8S76_RS04185
RRunclassified

953 628-955 217 nt · Forward (+)

Old locus H8S76_04185RefSeq WP_158587242.1
H8S76_RS04190GCF_014287615#H8S76_RS04190
HKClassicCurrent focus

955 232-957 079 nt · Forward (+)

Old locus H8S76_04190RefSeq WP_103730934.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0989299Run 6 · HK · 14 sequences
Representative sequenceGCF_003478165#DXA40_RS06030Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0989299

Simplified PFAM architecture for HKOC_0989299

PFAM domain coverage: 236 / 615 aa (38.4%)

1 aa615 aa
HAMP: 335-382 aaHAMPHis_kinase: 400-474 aaHis_kinaseHATPase_c: 496-608 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[335-382] | His_kinase[400-474] | HATPase_c[496-608]
  • Domain count: 3
  • Matched identifier: HKOC_0989299
  • Positioned domains: HAMP 335-382 ; His_kinase 400-474 ; HATPase_c 496-608
Cluster members and taxonomy
Visualization

Representative gene: GCF_003478165#DXA40_RS06030

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 763 026 · GCF_014287615
AssemblyASM1428761v1 · Contigreference genome · haploid
Genome composition6 189 697 bp · 46,5% GCBlautia celeris
Signal transduction countsGenes 263 · HK 136 · RR 124CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key