Gene detail

H8S76_RS04020

Histidine kinase, Hybrid

Blautia celeris · GCF_014287615

ClassHKTypeHybridLength1625 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_014287615#H8S76_RS04020Stable P2CS identifier used across views.
GenomeGCF_014287615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0039002Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_103731521.1 · A0ABR7F854 · MIST4 H8S76_RS04020RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

CheB_methylestMeTrcPAS_10PAS_3HisKAHATPase_cResponse_reg
Protein length1625 aaLength used to scale native and Biotite-like views.
Annotated domains88 with usable coordinates.
Domain coverage990 / 1625 aa (60.9%)Merged over positioned domains only.
Domain description1 CheB_methylest,1 MeTrc,1 PAS_10,2 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1625 aa
CheB_methylest: 23-198 aa (176 aa)1MeTrc: 221-461 aa (241 aa)2PAS_10: 731-835 aa (105 aa)3PAS_3: 867-954 aa (88 aa)4PAS_3: 1000-1079 aa (80 aa)5HisKA: 1245-1311 aa (67 aa)6HATPase_c: 1358-1473 aa (116 aa)7Response_reg: 1500-1616 aa (117 aa)8
Domain-by-domain annotation8 items
1 CheB_methylest#1
23-198 aa · 176 aa · 10.8% of protein
Raw tokenCheB_methylest:23:2.37e-64:198:177:177
2 MeTrc#2
221-461 aa · 241 aa · 14.8% of protein
Raw tokenMeTrc:221:2.5e-72:461:248:264
3 PAS_10#3
731-835 aa · 105 aa · 6.5% of protein
Raw tokenPAS_10:731:1.17e-21:835:105:106
4 PAS_3#4
867-954 aa · 88 aa · 5.4% of protein
Raw tokenPAS_3:867:0.00000000175:954:90:89
5 PAS_3#5
1000-1079 aa · 80 aa · 4.9% of protein
Raw tokenPAS_3:1000:0.00000000068:1079:80:89
6 HisKA#6
1245-1311 aa · 67 aa · 4.1% of protein
Raw tokenHisKA:1245:0.00000000000000135:1311:67:64
7 HATPase_c#7
1358-1473 aa · 116 aa · 7.1% of protein
Raw tokenHATPase_c:1358:3.26e-31:1473:116:109
8 Response_reg#8
1500-1616 aa · 117 aa · 7.2% of protein
Raw tokenResponse_reg:1500:3.53e-25:1616:117:111
  • Raw architecture: CheB_methylest:23:2.37e-64:198:177:177#MeTrc:221:2.5e-72:461:248:264#PAS_10:731:1.17e-21:835:105:106#PAS_3:867:0.00000000175:954:90:89#PAS_3:1000:0.00000000068:1079:80:89#HisKA:1245:0.00000000000000135:1311:67:64#HATPase_c:1358:3.26e-31:1473:116:109#Response_reg:1500:3.53e-25:1616:117:111
  • Domain description: 1 CheB_methylest,1 MeTrc,1 PAS_10,2 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_014287615::NZ_JACOOU010000001.1::G00026
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span901309-906186Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8S76_04020RefSeq proteinWP_103731521.1
Context group IDGCF_014287615::NZ_JACOOU010000001.1::G00026
Context members
H8S76_RS04020
Partner locus tags
H8S76_RS04020
Partner old locus tags
H8S76_04020
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_103731521.1Primary protein accession used for annex mappings.
UniProt accessionA0ABR7F854Primary UniProt accession resolved in the annex database.
UniProt IDA0ABR7F854_9FIRMDisplay identifier provided by UniProt.
GO / PubMed0 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8S76_RS04020Primary locus identifier stored in the genes table.
Old locus tagH8S76_04020Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOOU010000001.1Sequence record reported by the local genomic context database.
Genomic interval901 309-906 186 nt4 878 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span901 309-906 186 ntGCF_014287615::NZ_JACOOU010000001.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014287615::NZ_JACOOU010000001.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOOU010000001.1All displayed genes belong to this local TCS context.
Neighborhood span901 309-906 186 nt4 878 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
901 309 nt906 186 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

H8S76_RS04020GCF_014287615#H8S76_RS04020
HKHybridCurrent focus

901 309-906 186 nt · Forward (+)

Old locus H8S76_04020RefSeq WP_103731521.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0039002Run 6 · HK · 12 sequences
Representative sequenceGCF_003478165#DXA40_RS06205Use this link to inspect the representative gene detail.
PFAM architectureCheB_methylest + CheR_N + CheR + PAS_10 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg9 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0039002

Simplified PFAM architecture for HKOC_0039002

PFAM domain coverage: 980 / 1625 aa (60.3%)

1 aa1625 aa
CheB_methylest: 23-197 aaCheB_methylestCheR_N: 223-272 aaCheR: 288-475 aaCheRPAS_10: 731-835 aaPAS_10PAS_3: 868-948 aaPAS_3: 1000-1081 aaHisKA: 1246-1311 aaHATPase_c: 1358-1473 aaHATPase_cResponse_reg: 1500-1616 aaResponse_reg
CheB_methylestCheR_NCheRPAS_10PAS_3PAS_3HisKAHATPase_cResponse_reg
  • Simplified architecture: CheB_methylest + CheR_N + CheR + PAS_10 + PAS_3 + PAS_3 + HisKA + HATPase_c + Response_reg
  • Raw architecture: CheB_methylest[23-197] | CheR_N[223-272] | CheR[288-475] | PAS_10[731-835] | PAS_3[868-948] | PAS_3[1000-1081] | HisKA[1246-1311] | HATPase_c[1358-1473] | Response_reg[1500-1616]
  • Domain count: 9
  • Matched identifier: HKOC_0039002
  • Positioned domains: CheB_methylest 23-197 ; CheR_N 223-272 ; CheR 288-475 ; PAS_10 731-835 ; PAS_3 868-948 ; PAS_3 1000-1081 ; HisKA 1246-1311 ; HATPase_c 1358-1473 ; Response_reg 1500-1616
Cluster members and taxonomy
Visualization

Representative gene: GCF_003478165#DXA40_RS06205

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 763 026 · GCF_014287615
AssemblyASM1428761v1 · Contigreference genome · haploid
Genome composition6 189 697 bp · 46,5% GCBlautia celeris
Signal transduction countsGenes 263 · HK 136 · RR 124CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key