Gene detail

H8S76_RS00570

Histidine kinase, Classic

Blautia celeris · GCF_014287615

ClassHKTypeClassicLength622 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_014287615#H8S76_RS00570Stable P2CS identifier used across views.
GenomeGCF_014287615Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0967573Run 6 · 20 sequences · id 100% · cov 80%
External referencesWP_033140769.1 · A0ABR7F8Q1 · MIST4 H8S76_RS00570RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length622 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage366 / 622 aa (58.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa622 aa
dCache_1: 194-313 aa (120 aa)1HAMP: 330-396 aa (67 aa)2His_kinase: 414-493 aa (80 aa)3HATPase_c: 512-610 aa (99 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
194-313 aa · 120 aa · 19.3% of protein
Raw tokendCache_1:194:0.0000624:313:120:195
2 HAMP#2
330-396 aa · 67 aa · 10.8% of protein
Raw tokenHAMP:330:0.000000000000976:396:67:69
3 His_kinase#3
414-493 aa · 80 aa · 12.9% of protein
Raw tokenHis_kinase:414:6.77e-30:493:80:80
4 HATPase_c#4
512-610 aa · 99 aa · 15.9% of protein
Raw tokenHATPase_c:512:0.0000000495:610:109:109
  • Raw architecture: dCache_1:194:0.0000624:313:120:195#HAMP:330:0.000000000000976:396:67:69#His_kinase:414:6.77e-30:493:80:80#HATPase_c:512:0.0000000495:610:109:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_014287615::NZ_JACOOU010000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span122042-125447Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH8S76_00570RefSeq proteinWP_033140769.1
Context group IDGCF_014287615::NZ_JACOOU010000001.1::G00003
Context members
H8S76_RS00565H8S76_RS00570
Partner locus tags
H8S76_RS00565H8S76_RS00570
Partner old locus tags
H8S76_00565H8S76_00570
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_033140769.1Primary protein accession used for annex mappings.
UniProt accessionA0ABR7F8Q1Primary UniProt accession resolved in the annex database.
UniProt IDA0ABR7F8Q1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH8S76_RS00570Primary locus identifier stored in the genes table.
Old locus tagH8S76_00570Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JACOOU010000001.1Sequence record reported by the local genomic context database.
Genomic interval123 579-125 447 nt1 869 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span122 042-125 447 ntGCF_014287615::NZ_JACOOU010000001.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_014287615::NZ_JACOOU010000001.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JACOOU010000001.1All displayed genes belong to this local TCS context.
Neighborhood span122 042-125 447 nt3 406 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
122 042 nt125 447 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

H8S76_RS00565GCF_014287615#H8S76_RS00565
RRunclassified

122 042-123 601 nt · Reverse (-)

Old locus H8S76_00565RefSeq WP_033140770.1
H8S76_RS00570GCF_014287615#H8S76_RS00570
HKClassicCurrent focus

123 579-125 447 nt · Reverse (-)

Old locus H8S76_00570RefSeq WP_033140769.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0967573Run 6 · HK · 20 sequences
Representative sequenceGCF_003478165#DXA40_RS12750Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0967573

Simplified PFAM architecture for HKOC_0967573

PFAM domain coverage: 224 / 622 aa (36.0%)

1 aa622 aa
HAMP: 351-396 aaHAMPHis_kinase: 414-492 aaHis_kinaseHATPase_c: 511-609 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[351-396] | His_kinase[414-492] | HATPase_c[511-609]
  • Domain count: 3
  • Matched identifier: HKOC_0967573
  • Positioned domains: HAMP 351-396 ; His_kinase 414-492 ; HATPase_c 511-609
Cluster members and taxonomy
Visualization

Representative gene: GCF_003478165#DXA40_RS12750

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 2 763 026 · GCF_014287615
AssemblyASM1428761v1 · Contigreference genome · haploid
Genome composition6 189 697 bp · 46,5% GCBlautia celeris
Signal transduction countsGenes 263 · HK 136 · RR 124CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key