Gene detail

G4963_RS03240

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_013303595

ClassHKTypeClassicLength514 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013303595#G4963_RS03240Stable P2CS identifier used across views.
GenomeGCF_013303595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1411584Run 6 · 49 sequences · id 100% · cov 80%
External referencesWP_055168841.1 · A0A9Q4I2X0 · MIST4 G4963_RS03240RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length514 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage181 / 514 aa (35.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa514 aa
HisKA: 286-353 aa (68 aa)1HATPase_c: 397-509 aa (113 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
286-353 aa · 68 aa · 13.2% of protein
Raw tokenHisKA:286:0.0000000000013:353:68:64
2 HATPase_c#2
397-509 aa · 113 aa · 22.0% of protein
Raw tokenHATPase_c:397:9.79e-29:509:113:109
  • Raw architecture: HisKA:286:0.0000000000013:353:68:64#HATPase_c:397:9.79e-29:509:113:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013303595::NZ_JAAIRO010000003.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span62068-64309Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4963_03235RefSeq proteinWP_055168841.1
Context group IDGCF_013303595::NZ_JAAIRO010000003.1::G00032
Context members
G4963_RS03235G4963_RS03240
Partner locus tags
G4963_RS03235G4963_RS03240
Partner old locus tags
G4963_03230G4963_03235
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_055168841.1Primary protein accession used for annex mappings.
UniProt accessionA0A9Q4I2X0Primary UniProt accession resolved in the annex database.
UniProt IDA0A9Q4I2X0_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4963_RS03240Primary locus identifier stored in the genes table.
Old locus tagG4963_03235Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIRO010000003.1Sequence record reported by the local genomic context database.
Genomic interval62 765-64 309 nt1 545 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span62 068-64 309 ntGCF_013303595::NZ_JAAIRO010000003.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013303595::NZ_JAAIRO010000003.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIRO010000003.1All displayed genes belong to this local TCS context.
Neighborhood span62 068-64 309 nt2 242 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
62 068 nt64 309 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4963_RS03235GCF_013303595#G4963_RS03235
RROmpR

62 068-62 772 nt · Reverse (-)

Old locus G4963_03230RefSeq WP_004842962.1
G4963_RS03240GCF_013303595#G4963_RS03240
HKClassicCurrent focus

62 765-64 309 nt · Reverse (-)

Old locus G4963_03235RefSeq WP_055168841.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1411584Run 6 · HK · 49 sequences
Representative sequenceGCF_001406655#ARA00_RS07015Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1411584

Simplified PFAM architecture for HKOC_1411584

PFAM domain coverage: 286 / 514 aa (55.6%)

1 aa514 aa
DUF4118: 17-123 aaDUF4118HisKA: 286-353 aaHisKAHATPase_c: 398-508 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[17-123] | HisKA[286-353] | HATPase_c[398-508]
  • Domain count: 3
  • Matched identifier: HKOC_1411584
  • Positioned domains: DUF4118 17-123 ; HisKA 286-353 ; HATPase_c 398-508
Cluster members and taxonomy
Visualization

Representative gene: GCF_001406655#ARA00_RS07015

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_013303595
AssemblyASM1330359v1 · Contighaploid
Genome composition3 385 024 bp · 43,0% GCMediterraneibacter gnavus
Signal transduction countsGenes 90 · HK 43 · RR 46CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key