Gene detail

G4985_RS03075

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_013303585

ClassHKTypeClassicLength569 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013303585#G4985_RS03075Stable P2CS identifier used across views.
GenomeGCF_013303585Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1216849Run 6 · 64 sequences · id 100% · cov 80%
External referencesWP_009244102.1 · A0A829NTI0 · MIST4 G4985_RS03075RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length569 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage464 / 569 aa (81.5%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa569 aa
dCache_1: 48-264 aa (217 aa)1HAMP: 283-348 aa (66 aa)2His_kinase: 369-446 aa (78 aa)3HATPase_c: 462-564 aa (103 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
48-264 aa · 217 aa · 38.1% of protein
Raw tokendCache_1:48:0.000000000000105:264:228:195
2 HAMP#2
283-348 aa · 66 aa · 11.6% of protein
Raw tokenHAMP:283:0.00000362:348:67:69
3 His_kinase#3
369-446 aa · 78 aa · 13.7% of protein
Raw tokenHis_kinase:369:1.43e-26:446:78:80
4 HATPase_c#4
462-564 aa · 103 aa · 18.1% of protein
Raw tokenHATPase_c:462:0.00000000104:564:117:109
  • Raw architecture: dCache_1:48:0.000000000000105:264:228:195#HAMP:283:0.00000362:348:67:69#His_kinase:369:1.43e-26:446:78:80#HATPase_c:462:0.00000000104:564:117:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013303585::NZ_JAAIRN010000004.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span37244-40449Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4985_03080RefSeq proteinWP_009244102.1
Context group IDGCF_013303585::NZ_JAAIRN010000004.1::G00037
Context members
G4985_RS03075G4985_RS03080
Partner locus tags
G4985_RS03075G4985_RS03080
Partner old locus tags
G4985_03080G4985_03085
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009244102.1Primary protein accession used for annex mappings.
UniProt accessionA0A829NTI0Primary UniProt accession resolved in the annex database.
UniProt IDA0A829NTI0_MEDG5Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4985_RS03075Primary locus identifier stored in the genes table.
Old locus tagG4985_03080Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIRN010000004.1Sequence record reported by the local genomic context database.
Genomic interval37 244-38 953 nt1 710 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span37 244-40 449 ntGCF_013303585::NZ_JAAIRN010000004.1::G00037

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013303585::NZ_JAAIRN010000004.1::G00037

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIRN010000004.1All displayed genes belong to this local TCS context.
Neighborhood span37 244-40 449 nt3 206 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
37 244 nt40 449 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4985_RS03075GCF_013303585#G4985_RS03075
HKClassicCurrent focus

37 244-38 953 nt · Forward (+)

Old locus G4985_03080RefSeq WP_009244102.1
G4985_RS03080GCF_013303585#G4985_RS03080
RRunclassified

38 944-40 449 nt · Forward (+)

Old locus G4985_03085RefSeq WP_009244103.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1216849Run 6 · HK · 64 sequences
Representative sequenceGCF_000507805#HMPREF1201_RS08640Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1216849

Simplified PFAM architecture for HKOC_1216849

PFAM domain coverage: 178 / 569 aa (31.3%)

1 aa569 aa
His_kinase: 368-445 aaHis_kinaseHATPase_c: 464-563 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[368-445] | HATPase_c[464-563]
  • Domain count: 2
  • Matched identifier: HKOC_1216849
  • Positioned domains: His_kinase 368-445 ; HATPase_c 464-563
Cluster members and taxonomy
Visualization

Representative gene: GCF_000507805#HMPREF1201_RS08640

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_013303585
AssemblyASM1330358v1 · Contighaploid
Genome composition3 824 022 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 103 · HK 51 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key