Gene detail

G4978_RS06035

Histidine kinase, Classic

Mediterraneibacter gnavus · GCF_013303465

ClassHKTypeClassicLength572 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013303465#G4978_RS06035Stable P2CS identifier used across views.
GenomeGCF_013303465Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Mediterraneibacter
Selected clusterHKOC_1204019Run 6 · 10 sequences · id 100% · cov 80%
External referencesWP_226972096.1 · A0AAJ1B6N5 · MIST4 G4978_RS06035RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length572 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage459 / 572 aa (80.2%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa572 aa
dCache_1: 42-245 aa (204 aa)1HAMP: 281-351 aa (71 aa)2His_kinase: 367-446 aa (80 aa)3HATPase_c: 463-566 aa (104 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
42-245 aa · 204 aa · 35.7% of protein
Raw tokendCache_1:42:0.00000000536:245:208:195
2 HAMP#2
281-351 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:281:0.000000365:351:71:69
3 His_kinase#3
367-446 aa · 80 aa · 14.0% of protein
Raw tokenHis_kinase:367:2.84e-29:446:80:80
4 HATPase_c#4
463-566 aa · 104 aa · 18.2% of protein
Raw tokenHATPase_c:463:0.000000000000991:566:110:109
  • Raw architecture: dCache_1:42:0.00000000536:245:208:195#HAMP:281:0.000000365:351:71:69#His_kinase:367:2.84e-29:446:80:80#HATPase_c:463:0.000000000000991:566:110:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013303465::NZ_JAAIRI010000007.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span59156-62388Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4978_06000RefSeq proteinWP_226972096.1
Context group IDGCF_013303465::NZ_JAAIRI010000007.1::G00053
Context members
G4978_RS06030G4978_RS06035
Partner locus tags
G4978_RS06030G4978_RS06035
Partner old locus tags
G4978_05995G4978_06000
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_226972096.1Primary protein accession used for annex mappings.
UniProt accessionA0AAJ1B6N5Primary UniProt accession resolved in the annex database.
UniProt IDA0AAJ1B6N5_MEDGNDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4978_RS06035Primary locus identifier stored in the genes table.
Old locus tagG4978_06000Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIRI010000007.1Sequence record reported by the local genomic context database.
Genomic interval60 670-62 388 nt1 719 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span59 156-62 388 ntGCF_013303465::NZ_JAAIRI010000007.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013303465::NZ_JAAIRI010000007.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIRI010000007.1All displayed genes belong to this local TCS context.
Neighborhood span59 156-62 388 nt3 233 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
59 156 nt62 388 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4978_RS06030GCF_013303465#G4978_RS06030
RRunclassified

59 156-60 682 nt · Reverse (-)

Old locus G4978_05995RefSeq WP_117993778.1
G4978_RS06035GCF_013303465#G4978_RS06035
HKClassicCurrent focus

60 670-62 388 nt · Reverse (-)

Old locus G4978_06000RefSeq WP_226972096.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1204019Run 6 · HK · 10 sequences
Representative sequenceGCF_013303255#G4975_RS06020Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1204019

Simplified PFAM architecture for HKOC_1204019

PFAM domain coverage: 181 / 572 aa (31.6%)

1 aa572 aa
His_kinase: 367-446 aaHis_kinaseHATPase_c: 465-565 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[367-446] | HATPase_c[465-565]
  • Domain count: 2
  • Matched identifier: HKOC_1204019
  • Positioned domains: His_kinase 367-446 ; HATPase_c 465-565
Cluster members and taxonomy
Visualization

Representative gene: GCF_013303255#G4975_RS06020

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 33 038 · GCF_013303465
AssemblyASM1330346v1 · Contighaploid
Genome composition3 848 275 bp · 42,5% GCMediterraneibacter gnavus
Signal transduction countsGenes 107 · HK 52 · RR 54CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusMediterraneibacter
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Mediterraneibacter

Related genes

Preview from the same derived genome key