Gene detail

G4925_RS11335

Histidine kinase, Classic

Anaerostipes hadrus · GCF_013302665

ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013302665#G4925_RS11335Stable P2CS identifier used across views.
GenomeGCF_013302665Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_1665447Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_022091716.1 · A0A173SZ23 · MIST4 G4925_RS11335RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage227 / 475 aa (47.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
HAMP: 173-239 aa (67 aa)1HisKA: 251-303 aa (53 aa)2HATPase_c: 360-466 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
173-239 aa · 67 aa · 14.1% of protein
Raw tokenHAMP:173:0.00000000000000148:239:67:69
2 HisKA#2
251-303 aa · 53 aa · 11.2% of protein
Raw tokenHisKA:251:0.000000000189:303:53:64
3 HATPase_c#3
360-466 aa · 107 aa · 22.5% of protein
Raw tokenHATPase_c:360:2.61e-30:466:107:109
  • Raw architecture: HAMP:173:0.00000000000000148:239:67:69#HisKA:251:0.000000000189:303:53:64#HATPase_c:360:2.61e-30:466:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013302665::NZ_JAAIQK010000034.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27396-29479Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4925_11375RefSeq proteinWP_022091716.1
Context group IDGCF_013302665::NZ_JAAIQK010000034.1::G00018
Context members
G4925_RS11330G4925_RS11335
Partner locus tags
G4925_RS11330G4925_RS11335
Partner old locus tags
G4925_11370G4925_11375
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_022091716.1Primary protein accession used for annex mappings.
UniProt accessionA0A173SZ23Primary UniProt accession resolved in the annex database.
UniProt IDA0A173SZ23_ANAHADisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4925_RS11335Primary locus identifier stored in the genes table.
Old locus tagG4925_11375Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIQK010000034.1Sequence record reported by the local genomic context database.
Genomic interval28 052-29 479 nt1 428 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span27 396-29 479 ntGCF_013302665::NZ_JAAIQK010000034.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013302665::NZ_JAAIQK010000034.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIQK010000034.1All displayed genes belong to this local TCS context.
Neighborhood span27 396-29 479 nt2 084 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 396 nt29 479 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4925_RS11330GCF_013302665#G4925_RS11330
RROmpR

27 396-28 055 nt · Forward (+)

Old locus G4925_11370RefSeq WP_008392941.1
G4925_RS11335GCF_013302665#G4925_RS11335
HKClassicCurrent focus

28 052-29 479 nt · Forward (+)

Old locus G4925_11375RefSeq WP_022091716.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1665447Run 6 · HK · 5 sequences
Representative sequenceGCF_001405635#ARA30_RS07965Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1665447

Simplified PFAM architecture for HKOC_1665447

PFAM domain coverage: 212 / 475 aa (44.6%)

1 aa475 aa
HAMP: 187-238 aaHAMPHisKA: 251-303 aaHisKAHATPase_c: 360-466 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[187-238] | HisKA[251-303] | HATPase_c[360-466]
  • Domain count: 3
  • Matched identifier: HKOC_1665447
  • Positioned domains: HAMP 187-238 ; HisKA 251-303 ; HATPase_c 360-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_001405635#ARA30_RS07965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_013302665
AssemblyASM1330266v1 · Contighaploid
Genome composition2 988 393 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 54 · HK 27 · RR 26CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key