Gene detail

G4944_RS01880

Histidine kinase, Hybrid

Anaerostipes hadrus · GCF_013302555

ClassHKTypeHybridLength1051 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_013302555#G4944_RS01880Stable P2CS identifier used across views.
GenomeGCF_013302555Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0258886Run 6 · 7 sequences · id 100% · cov 80%
External referencesWP_173725218.1 · A0ABX2HUS1 · MIST4 G4944_RS01880RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GGDEFHisKAHATPase_cResponse_reg
Protein length1051 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage447 / 1051 aa (42.5%)Merged over positioned domains only.
Domain description1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1051 aa
GGDEF: 198-345 aa (148 aa)1HisKA: 672-738 aa (67 aa)2HATPase_c: 789-904 aa (116 aa)3Response_reg: 928-1043 aa (116 aa)4
Domain-by-domain annotation4 items
1 GGDEF#1
198-345 aa · 148 aa · 14.1% of protein
Raw tokenGGDEF:198:4.01e-22:345:157:160
2 HisKA#2
672-738 aa · 67 aa · 6.4% of protein
Raw tokenHisKA:672:0.00000000000000409:738:67:64
3 HATPase_c#3
789-904 aa · 116 aa · 11.0% of protein
Raw tokenHATPase_c:789:2.03e-28:904:117:109
4 Response_reg#4
928-1043 aa · 116 aa · 11.0% of protein
Raw tokenResponse_reg:928:2.79e-28:1043:116:111
  • Raw architecture: GGDEF:198:4.01e-22:345:157:160#HisKA:672:0.00000000000000409:738:67:64#HATPase_c:789:2.03e-28:904:117:109#Response_reg:928:2.79e-28:1043:116:111
  • Domain description: 1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_013302555::NZ_JAAIQE010000003.1::G00023
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span59120-62275Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4944_01885RefSeq proteinWP_173725218.1
Context group IDGCF_013302555::NZ_JAAIQE010000003.1::G00023
Context members
G4944_RS01880
Partner locus tags
G4944_RS01880
Partner old locus tags
G4944_01885
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_173725218.1Primary protein accession used for annex mappings.
UniProt accessionA0ABX2HUS1Primary UniProt accession resolved in the annex database.
UniProt IDA0ABX2HUS1_ANAHADisplay identifier provided by UniProt.
GO / PubMed0 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4944_RS01880Primary locus identifier stored in the genes table.
Old locus tagG4944_01885Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIQE010000003.1Sequence record reported by the local genomic context database.
Genomic interval59 120-62 275 nt3 156 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span59 120-62 275 ntGCF_013302555::NZ_JAAIQE010000003.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013302555::NZ_JAAIQE010000003.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIQE010000003.1All displayed genes belong to this local TCS context.
Neighborhood span59 120-62 275 nt3 156 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
59 120 nt62 275 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

G4944_RS01880GCF_013302555#G4944_RS01880
HKHybridCurrent focus

59 120-62 275 nt · Reverse (-)

Old locus G4944_01885RefSeq WP_173725218.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0258886Run 6 · HK · 7 sequences
Representative sequenceGCF_013302455#G4934_RS04800Use this link to inspect the representative gene detail.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0258886

Simplified PFAM architecture for HKOC_0258886

PFAM domain coverage: 446 / 1051 aa (42.4%)

1 aa1051 aa
GGDEF: 198-346 aaGGDEFHisKA: 672-738 aaHisKAHATPase_c: 789-903 aaHATPase_cResponse_reg: 928-1042 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[198-346] | HisKA[672-738] | HATPase_c[789-903] | Response_reg[928-1042]
  • Domain count: 4
  • Matched identifier: HKOC_0258886
  • Positioned domains: GGDEF 198-346 ; HisKA 672-738 ; HATPase_c 789-903 ; Response_reg 928-1042
Cluster members and taxonomy
Visualization

Representative gene: GCF_013302455#G4934_RS04800

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 756 · GCF_013302555
AssemblyASM1330255v1 · Contighaploid
Genome composition3 354 284 bp · 37,0% GCAnaerostipes hadrus
Signal transduction countsGenes 58 · HK 28 · RR 29CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key