Gene detail

G5A00_RS10170

Histidine kinase, Hybrid

Blautia wexlerae · GCF_013302125

ClassHKTypeHybridLength887 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013302125#G5A00_RS10170Stable P2CS identifier used across views.
GenomeGCF_013302125Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_0433264Run 6 · 15 sequences · id 100% · cov 80%
External referencesWP_161234349.1 · A0A6L8T8E8 · MIST4 G5A00_RS10170RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAFHisKAHATPase_cResponse_reg
Protein length887 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage418 / 887 aa (47.1%)Merged over positioned domains only.
Domain description1 GAF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa887 aa
GAF: 53-167 aa (115 aa)1HisKA: 512-578 aa (67 aa)2HATPase_c: 625-742 aa (118 aa)3Response_reg: 764-881 aa (118 aa)4
Domain-by-domain annotation4 items
1 GAF#1
53-167 aa · 115 aa · 13.0% of protein
Raw tokenGAF:53:0.00000801:167:115:133
2 HisKA#2
512-578 aa · 67 aa · 7.6% of protein
Raw tokenHisKA:512:0.0000000000000812:578:67:64
3 HATPase_c#3
625-742 aa · 118 aa · 13.3% of protein
Raw tokenHATPase_c:625:3.61e-25:742:119:109
4 Response_reg#4
764-881 aa · 118 aa · 13.3% of protein
Raw tokenResponse_reg:764:4.6e-28:881:118:111
  • Raw architecture: GAF:53:0.00000801:167:115:133#HisKA:512:0.0000000000000812:578:67:64#HATPase_c:625:3.61e-25:742:119:109#Response_reg:764:4.6e-28:881:118:111
  • Domain description: 1 GAF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013302125::NZ_JAAIPO010000031.1::G00047
Group size22 locus tags listed below.
HK / RR2 / 0Counts resolved for the local TCS neighborhood.
Context span10244-15004Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG5A00_10195RefSeq proteinWP_161234349.1
Context group IDGCF_013302125::NZ_JAAIPO010000031.1::G00047
Context members
G5A00_RS10170G5A00_RS10175
Partner locus tags
G5A00_RS10170G5A00_RS10175
Partner old locus tags
G5A00_10195G5A00_10200
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_161234349.1Primary protein accession used for annex mappings.
UniProt accessionA0A6L8T8E8Primary UniProt accession resolved in the annex database.
UniProt IDA0A6L8T8E8_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
GO terms
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG5A00_RS10170Primary locus identifier stored in the genes table.
Old locus tagG5A00_10195Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIPO010000031.1Sequence record reported by the local genomic context database.
Genomic interval10 244-12 907 nt2 664 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span10 244-15 004 ntGCF_013302125::NZ_JAAIPO010000031.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013302125::NZ_JAAIPO010000031.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIPO010000031.1All displayed genes belong to this local TCS context.
Neighborhood span10 244-15 004 nt4 761 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 244 nt15 004 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G5A00_RS10170GCF_013302125#G5A00_RS10170
HKHybridCurrent focus

10 244-12 907 nt · Forward (+)

Old locus G5A00_10195RefSeq WP_161234349.1
G5A00_RS10175GCF_013302125#G5A00_RS10175
HKHybrid

12 944-15 004 nt · Forward (+)

Old locus G5A00_10200RefSeq WP_173700068.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0433264Run 6 · HK · 15 sequences
Representative sequenceGCF_009876865#GT728_RS19170Use this link to inspect the representative gene detail.
PFAM architectureGAF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0433264

Simplified PFAM architecture for HKOC_0433264

PFAM domain coverage: 415 / 887 aa (46.8%)

1 aa887 aa
GAF: 51-166 aaGAFHisKA: 512-578 aaHisKAHATPase_c: 626-740 aaHATPase_cResponse_reg: 764-880 aaResponse_reg
GAFHisKAHATPase_cResponse_reg
  • Simplified architecture: GAF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GAF[51-166] | HisKA[512-578] | HATPase_c[626-740] | Response_reg[764-880]
  • Domain count: 4
  • Matched identifier: HKOC_0433264
  • Positioned domains: GAF 51-166 ; HisKA 512-578 ; HATPase_c 626-740 ; Response_reg 764-880
Cluster members and taxonomy
Visualization

Representative gene: GCF_009876865#GT728_RS19170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013302125
AssemblyASM1330212v1 · Contighaploid
Genome composition4 466 268 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 158 · HK 78 · RR 79CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key