Gene detail

G4459_RS11065

Histidine kinase, Classic

Blautia wexlerae · GCF_013301645

ClassHKTypeClassicLength601 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301645#G4459_RS11065Stable P2CS identifier used across views.
GenomeGCF_013301645Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1049411Run 6 · 13 sequences · id 100% · cov 80%
External referencesWP_226824641.1 · MIST4 G4459_RS11065RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length601 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage254 / 601 aa (42.3%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa601 aa
HAMP: 301-370 aa (70 aa)1His_kinase: 386-465 aa (80 aa)2HATPase_c: 485-588 aa (104 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
301-370 aa · 70 aa · 11.6% of protein
Raw tokenHAMP:301:0.0000000000843:370:70:69
2 His_kinase#2
386-465 aa · 80 aa · 13.3% of protein
Raw tokenHis_kinase:386:4.06e-27:465:80:80
3 HATPase_c#3
485-588 aa · 104 aa · 17.3% of protein
Raw tokenHATPase_c:485:0.0000000000000651:588:106:109
  • Raw architecture: HAMP:301:0.0000000000843:370:70:69#His_kinase:386:4.06e-27:465:80:80#HATPase_c:485:0.0000000000000651:588:106:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013301645::NZ_JAAIOS010000034.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span6876-10497Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4459_11035RefSeq proteinWP_226824641.1
Context group IDGCF_013301645::NZ_JAAIOS010000034.1::G00033
Context members
G4459_RS11060G4459_RS11065
Partner locus tags
G4459_RS11060G4459_RS11065
Partner old locus tags
G4459_11030G4459_11035
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_226824641.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4459_RS11065Primary locus identifier stored in the genes table.
Old locus tagG4459_11035Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOS010000034.1Sequence record reported by the local genomic context database.
Genomic interval8 692-10 497 nt1 806 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span6 876-10 497 ntGCF_013301645::NZ_JAAIOS010000034.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013301645::NZ_JAAIOS010000034.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOS010000034.1All displayed genes belong to this local TCS context.
Neighborhood span6 876-10 497 nt3 622 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
6 876 nt10 497 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4459_RS11060GCF_013301645#G4459_RS11060
RRunclassified

6 876-8 519 nt · Reverse (-)

Old locus G4459_11030RefSeq WP_118568931.1
G4459_RS11065GCF_013301645#G4459_RS11065
HKClassicCurrent focus

8 692-10 497 nt · Reverse (-)

Old locus G4459_11035RefSeq WP_226824641.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1049411Run 6 · HK · 13 sequences
Representative sequenceGCF_013299815#G4455_RS11620Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1049411

Simplified PFAM architecture for HKOC_1049411

PFAM domain coverage: 234 / 601 aa (38.9%)

1 aa601 aa
HAMP: 318-370 aaHAMPHis_kinase: 387-463 aaHis_kinaseHATPase_c: 486-589 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[318-370] | His_kinase[387-463] | HATPase_c[486-589]
  • Domain count: 3
  • Matched identifier: HKOC_1049411
  • Positioned domains: HAMP 318-370 ; His_kinase 387-463 ; HATPase_c 486-589
Cluster members and taxonomy
Visualization

Representative gene: GCF_013299815#G4455_RS11620

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301645
AssemblyASM1330164v1 · Contighaploid
Genome composition4 078 636 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 126 · HK 63 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key