Gene detail

G4459_RS04345

Histidine kinase, Classic

Blautia wexlerae · GCF_013301645

ClassHKTypeClassicLength595 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013301645#G4459_RS04345Stable P2CS identifier used across views.
GenomeGCF_013301645Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Blautia
Selected clusterHKOC_1082862Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_173684313.1 · MIST4 G4459_RS04345RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length595 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 595 aa (43.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa595 aa
HAMP: 289-362 aa (74 aa)1His_kinase: 379-457 aa (79 aa)2HATPase_c: 477-581 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
289-362 aa · 74 aa · 12.4% of protein
Raw tokenHAMP:289:0.00000000000609:362:75:69
2 His_kinase#2
379-457 aa · 79 aa · 13.3% of protein
Raw tokenHis_kinase:379:4.22e-33:457:79:80
3 HATPase_c#3
477-581 aa · 105 aa · 17.6% of protein
Raw tokenHATPase_c:477:0.000000000000277:581:109:109
  • Raw architecture: HAMP:289:0.00000000000609:362:75:69#His_kinase:379:4.22e-33:457:79:80#HATPase_c:477:0.000000000000277:581:109:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013301645::NZ_JAAIOS010000008.1::G00073
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span60277-63616Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4459_04330RefSeq proteinWP_173684313.1
Context group IDGCF_013301645::NZ_JAAIOS010000008.1::G00073
Context members
G4459_RS04345G4459_RS04350
Partner locus tags
G4459_RS04345G4459_RS04350
Partner old locus tags
G4459_04330G4459_04335
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_173684313.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4459_RS04345Primary locus identifier stored in the genes table.
Old locus tagG4459_04330Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAIOS010000008.1Sequence record reported by the local genomic context database.
Genomic interval60 277-62 064 nt1 788 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span60 277-63 616 ntGCF_013301645::NZ_JAAIOS010000008.1::G00073

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013301645::NZ_JAAIOS010000008.1::G00073

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAIOS010000008.1All displayed genes belong to this local TCS context.
Neighborhood span60 277-63 616 nt3 340 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
60 277 nt63 616 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4459_RS04345GCF_013301645#G4459_RS04345
HKClassicCurrent focus

60 277-62 064 nt · Forward (+)

Old locus G4459_04330RefSeq WP_173684313.1
G4459_RS04350GCF_013301645#G4459_RS04350
RRunclassified

62 057-63 616 nt · Forward (+)

Old locus G4459_04335RefSeq WP_173684314.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1082862Run 6 · HK · 5 sequences
Representative sequenceGCF_013301625#G4538_RS01245Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1082862

Simplified PFAM architecture for HKOC_1082862

PFAM domain coverage: 182 / 595 aa (30.6%)

1 aa595 aa
His_kinase: 379-455 aaHis_kinaseHATPase_c: 476-580 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[379-455] | HATPase_c[476-580]
  • Domain count: 2
  • Matched identifier: HKOC_1082862
  • Positioned domains: His_kinase 379-455 ; HATPase_c 476-580
Cluster members and taxonomy
Visualization

Representative gene: GCF_013301625#G4538_RS01245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 418 240 · GCF_013301645
AssemblyASM1330164v1 · Contighaploid
Genome composition4 078 636 bp · 41,0% GCBlautia wexlerae
Signal transduction countsGenes 126 · HK 63 · RR 62CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusBlautia
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Blautia

Related genes

Preview from the same derived genome key