Gene detail

G4352_RS00305

Histidine kinase, Classic

Dorea longicatena · GCF_013300365

ClassHKTypeClassicLength577 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_013300365#G4352_RS00305Stable P2CS identifier used across views.
GenomeGCF_013300365Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Dorea
Selected clusterHKOC_1177298Run 6 · 31 sequences · id 100% · cov 80%
External referencesWP_006428464.1 · A6BDK0 · MIST4 G4352_RS00305RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length577 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage449 / 577 aa (77.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa577 aa
dCache_1: 37-230 aa (194 aa)1HAMP: 285-354 aa (70 aa)2His_kinase: 369-446 aa (78 aa)3HATPase_c: 465-571 aa (107 aa)4
Domain-by-domain annotation4 items
1 dCache_1#1
37-230 aa · 194 aa · 33.6% of protein
Raw tokendCache_1:37:0.0000138:230:195:195
2 HAMP#2
285-354 aa · 70 aa · 12.1% of protein
Raw tokenHAMP:285:0.00000000000000135:354:70:69
3 His_kinase#3
369-446 aa · 78 aa · 13.5% of protein
Raw tokenHis_kinase:369:1.87e-26:446:78:80
4 HATPase_c#4
465-571 aa · 107 aa · 18.5% of protein
Raw tokenHATPase_c:465:0.00000000000872:571:111:109
  • Raw architecture: dCache_1:37:0.0000138:230:195:195#HAMP:285:0.00000000000000135:354:70:69#His_kinase:369:1.87e-26:446:78:80#HATPase_c:465:0.00000000000872:571:111:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_013300365::NZ_JAAILM010000001.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span62578-65960Genomic interval covered by the local TCS group.
Identifiers
Old locus tagG4352_00305RefSeq proteinWP_006428464.1
Context group IDGCF_013300365::NZ_JAAILM010000001.1::G00012
Context members
G4352_RS00300G4352_RS00305
Partner locus tags
G4352_RS00300G4352_RS00305
Partner old locus tags
G4352_00300G4352_00305
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_006428464.1Primary protein accession used for annex mappings.
UniProt accessionA6BDK0Primary UniProt accession resolved in the annex database.
UniProt IDA6BDK0_9FIRMDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagG4352_RS00305Primary locus identifier stored in the genes table.
Old locus tagG4352_00305Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAILM010000001.1Sequence record reported by the local genomic context database.
Genomic interval64 227-65 960 nt1 734 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span62 578-65 960 ntGCF_013300365::NZ_JAAILM010000001.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_013300365::NZ_JAAILM010000001.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAILM010000001.1All displayed genes belong to this local TCS context.
Neighborhood span62 578-65 960 nt3 383 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
62 578 nt65 960 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

G4352_RS00300GCF_013300365#G4352_RS00300
RRunclassified

62 578-64 230 nt · Reverse (-)

Old locus G4352_00300RefSeq WP_006428465.1
G4352_RS00305GCF_013300365#G4352_RS00305
HKClassicCurrent focus

64 227-65 960 nt · Reverse (-)

Old locus G4352_00305RefSeq WP_006428464.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1177298Run 6 · HK · 31 sequences
Representative sequenceGCF_000154065#DORLON_RS11400Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1177298

Simplified PFAM architecture for HKOC_1177298

PFAM domain coverage: 236 / 577 aa (40.9%)

1 aa577 aa
HAMP: 303-354 aaHAMPHis_kinase: 369-446 aaHis_kinaseHATPase_c: 465-570 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[303-354] | His_kinase[369-446] | HATPase_c[465-570]
  • Domain count: 3
  • Matched identifier: HKOC_1177298
  • Positioned domains: HAMP 303-354 ; His_kinase 369-446 ; HATPase_c 465-570
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154065#DORLON_RS11400

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 88 431 · GCF_013300365
AssemblyASM1330036v1 · Contighaploid
Genome composition3 342 606 bp · 41,0% GCDorea longicatena
Signal transduction countsGenes 90 · HK 44 · RR 45CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusDorea
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Dorea

Related genes

Preview from the same derived genome key