1 PAS_8#1
358-395 aa · 38 aa · 5.1% of protein
Raw token
PAS_8:358:0.0000441:395:38:65P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
GSQ44_RS18505
Histidine kinase, Classic
Clostridioides difficile · GCF_012276965
ClassHKTypeClassicLength738 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_012276965#GSQ44_RS18505Stable P2CS identifier used across views.
GenomeGCF_012276965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_8HisKAHATPase_c
Protein length738 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 738 aa (30.1%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa738 aa
Domain-by-domain annotation3 items
2 HisKA#2
481-552 aa · 72 aa · 9.8% of protein
Raw token
HisKA:481:0.00000000127:552:72:643 HATPase_c#3
600-711 aa · 112 aa · 15.2% of protein
Raw token
HATPase_c:600:1.27e-25:711:112:109- Raw architecture: PAS_8:358:0.0000441:395:38:65#HisKA:481:0.00000000127:552:72:64#HATPase_c:600:1.27e-25:711:112:109
- Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_012276965::NZ_JAAXLO010000235.1::G00025
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span765-2982Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ44_18570RefSeq proteinWP_168318287.1
Context group ID
GCF_012276965::NZ_JAAXLO010000235.1::G00025Context members
GSQ44_RS18505
Partner locus tags
GSQ44_RS18505
Partner old locus tags
GSQ44_18570
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_168318287.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagGSQ44_RS18505Primary locus identifier stored in the genes table.
Old locus tagGSQ44_18570Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAXLO010000235.1Sequence record reported by the local genomic context database.
Genomic interval765-2 982 nt2 218 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span765-2 982 ntGCF_012276965::NZ_JAAXLO010000235.1::G00025
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_012276965::NZ_JAAXLO010000235.1::G00025Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAXLO010000235.1All displayed genes belong to this local TCS context.
Neighborhood span765-2 982 nt2 218 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
765 nt2 982 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
GSQ44_RS18505GCF_012276965#GSQ44_RS18505
HKClassicCurrent focus
765-2 982 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_012276965#GSQ44_RS18505The current gene is the representative for this cluster.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0696293
Simplified PFAM architecture for HKOC_0696293
PFAM domain coverage: 221 / 738 aa (29.9%)
1 aa738 aa
PAS_8HisKAHATPase_c
- Simplified architecture: PAS_8 + HisKA + HATPase_c
- Raw architecture: PAS_8[358-398] | HisKA[482-550] | HATPase_c[600-710]
- Domain count: 3
- Matched identifier: HKOC_0696293
- Positioned domains: PAS_8 358-398 ; HisKA 482-550 ; HATPase_c 600-710
Cluster members and taxonomy
Representative gene: GCF_012276965#GSQ44_RS18505
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_012276965
AssemblyASM1227696v1 · Contighaploid
Genome composition4 129 981 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 43 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key