Gene detail

GSQ44_RS06060

Histidine kinase, Classic

Clostridioides difficile · GCF_012276965

ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012276965#GSQ44_RS06060Stable P2CS identifier used across views.
GenomeGCF_012276965Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2883601Run 6 · 969 sequences · id 100% · cov 80%
External referencesWP_003435311.1 · A0A9X8RGV3 · MIST4 GSQ44_RS06060RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
HisKA: 82-144 aa (63 aa)1HATPase_c: 196-295 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw tokenHisKA:82:0.0000000761:144:63:64
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw tokenHATPase_c:196:2.39e-22:295:100:109
  • Raw architecture: HisKA:82:0.0000000761:144:63:64#HATPase_c:196:2.39e-22:295:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012276965::NZ_JAAXLO010000024.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span7843-9424Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ44_06075RefSeq proteinWP_003435311.1
Context group IDGCF_012276965::NZ_JAAXLO010000024.1::G00027
Context members
GSQ44_RS06060GSQ44_RS06065
Partner locus tags
GSQ44_RS06060GSQ44_RS06065
Partner old locus tags
GSQ44_06075GSQ44_06080
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003435311.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RGV3Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RGV3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ44_RS06060Primary locus identifier stored in the genes table.
Old locus tagGSQ44_06075Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAXLO010000024.1Sequence record reported by the local genomic context database.
Genomic interval7 843-8 751 nt909 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span7 843-9 424 ntGCF_012276965::NZ_JAAXLO010000024.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012276965::NZ_JAAXLO010000024.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAXLO010000024.1All displayed genes belong to this local TCS context.
Neighborhood span7 843-9 424 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 843 nt9 424 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ44_RS06060GCF_012276965#GSQ44_RS06060
HKClassicCurrent focus

7 843-8 751 nt · Reverse (-)

Old locus GSQ44_06075RefSeq WP_003435311.1
GSQ44_RS06065GCF_012276965#GSQ44_RS06065
RROmpR

8 753-9 424 nt · Reverse (-)

Old locus GSQ44_06080RefSeq WP_009897090.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2883601Run 6 · HK · 969 sequences
Representative sequenceGCF_033840375#SIK50_RS12330Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2883601

Simplified PFAM architecture for HKOC_2883601

PFAM domain coverage: 165 / 304 aa (54.3%)

1 aa304 aa
HisKA: 84-146 aaHisKAHATPase_c: 197-298 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[84-146] | HATPase_c[197-298]
  • Domain count: 2
  • Matched identifier: HKOC_2883601
  • Positioned domains: HisKA 84-146 ; HATPase_c 197-298
Cluster members and taxonomy
Visualization

Representative gene: GCF_033840375#SIK50_RS12330

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012276965
AssemblyASM1227696v1 · Contighaploid
Genome composition4 129 981 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 43 · RR 49CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key