Gene detail

GSQ43_RS13660

Histidine kinase, Classic

Clostridioides difficile · GCF_012030175

ClassHKTypeClassicLength535 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012030175#GSQ43_RS13660Stable P2CS identifier used across views.
GenomeGCF_012030175Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338674Run 6 · 39 sequences · id 100% · cov 80%
External referencesWP_021374542.1 · MIST4 GSQ43_RS13660RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length535 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 535 aa (33.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa535 aa
HisKA: 304-371 aa (68 aa)1HATPase_c: 416-525 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 12.7% of protein
Raw tokenHisKA:304:0.000000000000132:371:68:64
2 HATPase_c#2
416-525 aa · 110 aa · 20.6% of protein
Raw tokenHATPase_c:416:2.77e-31:525:110:109
  • Raw architecture: HisKA:304:0.000000000000132:371:68:64#HATPase_c:416:2.77e-31:525:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012030175::NZ_JAAUXG010000092.1::G00056
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span12454-14756Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ43_13640RefSeq proteinWP_021374542.1
Context group IDGCF_012030175::NZ_JAAUXG010000092.1::G00056
Context members
GSQ43_RS13660GSQ43_RS13665
Partner locus tags
GSQ43_RS13660GSQ43_RS13665
Partner old locus tags
GSQ43_13640GSQ43_13645
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021374542.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ43_RS13660Primary locus identifier stored in the genes table.
Old locus tagGSQ43_13640Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAAUXG010000092.1Sequence record reported by the local genomic context database.
Genomic interval12 454-14 061 nt1 608 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span12 454-14 756 ntGCF_012030175::NZ_JAAUXG010000092.1::G00056

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012030175::NZ_JAAUXG010000092.1::G00056

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAAUXG010000092.1All displayed genes belong to this local TCS context.
Neighborhood span12 454-14 756 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
12 454 nt14 756 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ43_RS13660GCF_012030175#GSQ43_RS13660
HKClassicCurrent focus

12 454-14 061 nt · Forward (+)

Old locus GSQ43_13640RefSeq WP_021374542.1
GSQ43_RS13665GCF_012030175#GSQ43_RS13665
RROmpR

14 052-14 756 nt · Forward (+)

Old locus GSQ43_13645RefSeq WP_021374494.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338674Run 6 · HK · 39 sequences
Representative sequenceGCF_000449185#QCW_RS02610Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338674

Simplified PFAM architecture for HKOC_1338674

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338674
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449185#QCW_RS02610

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012030175
AssemblyASM1203017v1 · Contighaploid
Genome composition4 172 576 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 43 · RR 51CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key