Gene detail

GSQ35_RS04040

Histidine kinase, Hybrid

Clostridioides difficile · GCF_012029905

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_012029905#GSQ35_RS04040Stable P2CS identifier used across views.
GenomeGCF_012029905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0485211Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_167653827.1 · MIST4 GSQ35_RS04040RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage409 / 852 aa (48.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa852 aa
HisKA: 344-410 aa (67 aa)1HATPase_c: 458-576 aa (119 aa)2Response_reg: 592-696 aa (105 aa)3Response_reg: 731-848 aa (118 aa)4
Domain-by-domain annotation4 items
1 HisKA#1
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:7.39e-18:410:67:64
2 HATPase_c#2
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:4.67e-25:576:120:109
3 Response_reg#3
592-696 aa · 105 aa · 12.3% of protein
Raw tokenResponse_reg:592:3.15e-22:696:105:111
4 Response_reg#4
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:5.44e-27:848:118:111
  • Raw architecture: HisKA:344:7.39e-18:410:67:64#HATPase_c:458:4.67e-25:576:120:109#Response_reg:592:3.15e-22:696:105:111#Response_reg:731:5.44e-27:848:118:111
  • Domain description: 1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_012029905::NZ_JAATWN010000008.1::G00050
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span64743-69311Genomic interval covered by the local TCS group.
Identifiers
Old locus tagGSQ35_04040RefSeq proteinWP_167653827.1
Context group IDGCF_012029905::NZ_JAATWN010000008.1::G00050
Context members
GSQ35_RS04040GSQ35_RS04050
Partner locus tags
GSQ35_RS04040GSQ35_RS04050
Partner old locus tags
GSQ35_04040GSQ35_04050
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_167653827.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagGSQ35_RS04040Primary locus identifier stored in the genes table.
Old locus tagGSQ35_04040Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JAATWN010000008.1Sequence record reported by the local genomic context database.
Genomic interval64 743-67 301 nt2 559 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span64 743-69 311 ntGCF_012029905::NZ_JAATWN010000008.1::G00050

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_012029905::NZ_JAATWN010000008.1::G00050

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JAATWN010000008.1All displayed genes belong to this local TCS context.
Neighborhood span64 743-69 311 nt4 569 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
64 743 nt69 311 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

GSQ35_RS04040GCF_012029905#GSQ35_RS04040
HKHybridCurrent focus

64 743-67 301 nt · Reverse (-)

Old locus GSQ35_04040RefSeq WP_167653827.1
GSQ35_RS04050GCF_012029905#GSQ35_RS04050
RRRpfG

67 671-69 311 nt · Reverse (-)

Old locus GSQ35_04050RefSeq WP_009901919.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0485211Run 6 · HK · 8 sequences
Representative sequenceGCF_012029905#GSQ35_RS04040The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0485211

Simplified PFAM architecture for HKOC_0485211

PFAM domain coverage: 413 / 852 aa (48.5%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-702 aaResponse_regResponse_reg: 731-847 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-702] | Response_reg[731-847]
  • Domain count: 4
  • Matched identifier: HKOC_0485211
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-702 ; Response_reg 731-847
Cluster members and taxonomy
Visualization

Representative gene: GCF_012029905#GSQ35_RS04040

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_012029905
AssemblyASM1202990v1 · Contighaploid
Genome composition4 045 570 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 92 · HK 41 · RR 49CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key