Gene detail

DNC28_RS04165

Histidine kinase, Classic

Clostridioides difficile · GCF_009903535

ClassHKTypeClassicLength334 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_009903535#DNC28_RS04165Stable P2CS identifier used across views.
GenomeGCF_009903535Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2849747Run 6 · 1514 sequences · id 100% · cov 80%
External referencesWP_003436739.1 · Q18C51 · MIST4 DNC28_RS04165RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length334 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage169 / 334 aa (50.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa334 aa
HisKA: 118-178 aa (61 aa)1HATPase_c: 224-331 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
118-178 aa · 61 aa · 18.3% of protein
Raw tokenHisKA:118:0.00000764:178:63:64
2 HATPase_c#2
224-331 aa · 108 aa · 32.3% of protein
Raw tokenHATPase_c:224:2.89e-25:331:108:109
  • Raw architecture: HisKA:118:0.00000764:178:63:64#HATPase_c:224:2.89e-25:331:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_009903535::NZ_QKRE01000004.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span703955-705657Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDNC28_04280RefSeq proteinWP_003436739.1
Context group IDGCF_009903535::NZ_QKRE01000004.1::G00008
Context members
DNC28_RS04165DNC28_RS04170
Partner locus tags
DNC28_RS04165DNC28_RS04170
Partner old locus tags
DNC28_04280DNC28_04285
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003436739.1Primary protein accession used for annex mappings.
UniProt accessionQ18C51Primary UniProt accession resolved in the annex database.
UniProt IDQ18C51_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDNC28_RS04165Primary locus identifier stored in the genes table.
Old locus tagDNC28_04280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QKRE01000004.1Sequence record reported by the local genomic context database.
Genomic interval703 955-704 959 nt1 005 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span703 955-705 657 ntGCF_009903535::NZ_QKRE01000004.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_009903535::NZ_QKRE01000004.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QKRE01000004.1All displayed genes belong to this local TCS context.
Neighborhood span703 955-705 657 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
703 955 nt705 657 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DNC28_RS04165GCF_009903535#DNC28_RS04165
HKClassicCurrent focus

703 955-704 959 nt · Reverse (-)

Old locus DNC28_04280RefSeq WP_003436739.1
DNC28_RS04170GCF_009903535#DNC28_RS04170
RROmpR

704 983-705 657 nt · Reverse (-)

Old locus DNC28_04285RefSeq WP_003436727.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2849747Run 6 · HK · 1514 sequences
Representative sequenceGCF_000009205#CD630_RS08375Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2849747

Simplified PFAM architecture for HKOC_2849747

PFAM domain coverage: 108 / 334 aa (32.3%)

1 aa334 aa
HATPase_c: 224-331 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[224-331]
  • Domain count: 1
  • Matched identifier: HKOC_2849747
  • Positioned domains: HATPase_c 224-331
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009205#CD630_RS08375

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_009903535
AssemblyASM990353v1 · Contighaploid
Genome composition4 390 781 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 107 · HK 51 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key