Gene detail

F6C11_RS03715

Histidine kinase, Classic

Clostridioides difficile · GCF_008579085

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_008579085#F6C11_RS03715Stable P2CS identifier used across views.
GenomeGCF_008579085Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557654Run 6 · 299 sequences · id 100% · cov 80%
External referencesWP_003417817.1 · D5Q091 · MIST4 F6C11_RS03715RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 386 aa (59.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HAMP: 84-152 aa (69 aa)1HisKA: 164-217 aa (54 aa)2HATPase_c: 278-382 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
84-152 aa · 69 aa · 17.9% of protein
Raw tokenHAMP:84:0.000000527:152:70:69
2 HisKA#2
164-217 aa · 54 aa · 14.0% of protein
Raw tokenHisKA:164:0.0000000445:217:54:64
3 HATPase_c#3
278-382 aa · 105 aa · 27.2% of protein
Raw tokenHATPase_c:278:1.65e-20:382:106:109
  • Raw architecture: HAMP:84:0.000000527:152:70:69#HisKA:164:0.0000000445:217:54:64#HATPase_c:278:1.65e-20:382:106:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_008579085::NZ_BEHB01000003.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span189190-191012Genomic interval covered by the local TCS group.
Identifiers
Old locus tagTNHP173_07240RefSeq proteinWP_003417817.1
Context group IDGCF_008579085::NZ_BEHB01000003.1::G00010
Context members
F6C11_RS03715F6C11_RS03720
Partner locus tags
F6C11_RS03715F6C11_RS03720
Partner old locus tags
TNHP173_07240TNHP173_07250
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003417817.1Primary protein accession used for annex mappings.
UniProt accessionD5Q091Primary UniProt accession resolved in the annex database.
UniProt IDD5Q091_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagF6C11_RS03715Primary locus identifier stored in the genes table.
Old locus tagTNHP173_07240Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_BEHB01000003.1Sequence record reported by the local genomic context database.
Genomic interval189 190-190 350 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span189 190-191 012 ntGCF_008579085::NZ_BEHB01000003.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_008579085::NZ_BEHB01000003.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BEHB01000003.1All displayed genes belong to this local TCS context.
Neighborhood span189 190-191 012 nt1 823 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
189 190 nt191 012 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

F6C11_RS03715GCF_008579085#F6C11_RS03715
HKClassicCurrent focus

189 190-190 350 nt · Reverse (-)

Old locus TNHP173_07240RefSeq WP_003417817.1
F6C11_RS03720GCF_008579085#F6C11_RS03720
RROmpR

190 338-191 012 nt · Reverse (-)

Old locus TNHP173_07250RefSeq WP_003417819.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557654Run 6 · HK · 299 sequences
Representative sequenceGCF_000155065#QAE_RS0202410Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557654

Simplified PFAM architecture for HKOC_2557654

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557654
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0202410

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_008579085
AssemblyASM857908v1 · Contighaploid
Genome composition3 975 570 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key