Gene detail

FLH49_RS05805

Histidine kinase, Classic

Clostridioides difficile · GCF_007114985

ClassHKTypeClassicLength442 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007114985#FLH49_RS05805Stable P2CS identifier used across views.
GenomeGCF_007114985Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2054488Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_144017265.1 · MIST4 FLH49_RS05805RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length442 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage230 / 442 aa (52.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa442 aa
HAMP: 144-211 aa (68 aa)1HisKA: 231-296 aa (66 aa)2HATPase_c: 342-437 aa (96 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
144-211 aa · 68 aa · 15.4% of protein
Raw tokenHAMP:144:0.000000173:211:68:69
2 HisKA#2
231-296 aa · 66 aa · 14.9% of protein
Raw tokenHisKA:231:0.000000294:296:66:64
3 HATPase_c#3
342-437 aa · 96 aa · 21.7% of protein
Raw tokenHATPase_c:342:0.0000000000316:437:104:109
  • Raw architecture: HAMP:144:0.000000173:211:68:69#HisKA:231:0.000000294:296:66:64#HATPase_c:342:0.0000000000316:437:104:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007114985::NZ_VING01000003.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span113334-115315Genomic interval covered by the local TCS group.
Context group IDGCF_007114985::NZ_VING01000003.1::G00029
Context members
FLH49_RS05805FLH49_RS05810
Partner locus tags
FLH49_RS05805FLH49_RS05810
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_144017265.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFLH49_RS05805Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VING01000003.1Sequence record reported by the local genomic context database.
Genomic interval113 334-114 662 nt1 329 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span113 334-115 315 ntGCF_007114985::NZ_VING01000003.1::G00029

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007114985::NZ_VING01000003.1::G00029

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VING01000003.1All displayed genes belong to this local TCS context.
Neighborhood span113 334-115 315 nt1 982 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
113 334 nt115 315 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FLH49_RS05810GCF_007114985#FLH49_RS05810
RROmpR

114 659-115 315 nt · Reverse (-)

RefSeq WP_008790770.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2054488Run 6 · HK · 2 sequences
Representative sequenceGCF_007114985#FLH49_RS05805The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2054488

Simplified PFAM architecture for HKOC_2054488

PFAM domain coverage: 160 / 442 aa (36.2%)

1 aa442 aa
HisKA: 232-295 aaHisKAHATPase_c: 342-437 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[232-295] | HATPase_c[342-437]
  • Domain count: 2
  • Matched identifier: HKOC_2054488
  • Positioned domains: HisKA 232-295 ; HATPase_c 342-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_007114985#FLH49_RS05805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114985
AssemblyASM711498v1 · Scaffoldhaploid
Genome composition4 139 090 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key