Gene detail

FLH71_RS08855

Histidine kinase, Classic

Clostridioides difficile · GCF_007114945

ClassHKTypeClassicLength474 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007114945#FLH71_RS08855Stable P2CS identifier used across views.
GenomeGCF_007114945Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1678347Run 6 · 8 sequences · id 100% · cov 80%
External referencesWP_074136624.1 · MIST4 FLH71_RS08855RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length474 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 474 aa (53.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa474 aa
HAMP: 161-238 aa (78 aa)1HisKA: 250-315 aa (66 aa)2HATPase_c: 365-471 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-238 aa · 78 aa · 16.5% of protein
Raw tokenHAMP:161:0.0000000134:238:78:69
2 HisKA#2
250-315 aa · 66 aa · 13.9% of protein
Raw tokenHisKA:250:0.00000000169:315:66:64
3 HATPase_c#3
365-471 aa · 107 aa · 22.6% of protein
Raw tokenHATPase_c:365:3.21e-26:471:107:109
  • Raw architecture: HAMP:161:0.0000000134:238:78:69#HisKA:250:0.00000000169:315:66:64#HATPase_c:365:3.21e-26:471:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007114945::NZ_VINE01000004.1::G00048
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span132249-134384Genomic interval covered by the local TCS group.
Context group IDGCF_007114945::NZ_VINE01000004.1::G00048
Context members
FLH71_RS08855FLH71_RS08860
Partner locus tags
FLH71_RS08855FLH71_RS08860
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074136624.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFLH71_RS08855Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VINE01000004.1Sequence record reported by the local genomic context database.
Genomic interval132 249-133 673 nt1 425 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span132 249-134 384 ntGCF_007114945::NZ_VINE01000004.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007114945::NZ_VINE01000004.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VINE01000004.1All displayed genes belong to this local TCS context.
Neighborhood span132 249-134 384 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
132 249 nt134 384 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FLH71_RS08860GCF_007114945#FLH71_RS08860
RROmpR

133 692-134 384 nt · Reverse (-)

RefSeq WP_003434748.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1678347Run 6 · HK · 8 sequences
Representative sequenceGCF_007114585#FLH52_RS14165Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1678347

Simplified PFAM architecture for HKOC_1678347

PFAM domain coverage: 223 / 474 aa (47.0%)

1 aa474 aa
HAMP: 188-238 aaHAMPHisKA: 251-315 aaHisKAHATPase_c: 365-471 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[188-238] | HisKA[251-315] | HATPase_c[365-471]
  • Domain count: 3
  • Matched identifier: HKOC_1678347
  • Positioned domains: HAMP 188-238 ; HisKA 251-315 ; HATPase_c 365-471
Cluster members and taxonomy
Visualization

Representative gene: GCF_007114585#FLH52_RS14165

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114945
AssemblyASM711494v1 · Contighaploid
Genome composition4 310 585 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 51 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key