Gene detail

FLH82_RS02185

Histidine kinase, Classic

Clostridioides difficile · GCF_007114935

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007114935#FLH82_RS02185Stable P2CS identifier used across views.
GenomeGCF_007114935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293402Run 6 · 360 sequences · id 100% · cov 80%
External referencesWP_012816133.1 · A0A0H3N1Q8 · MIST4 FLH82_RS02185RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for FLH82_RS02185
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.000000000946:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:1.63e-21:410:107:109
  • Raw architecture: HisKA:199:0.000000000946:258:60:64#HATPase_c:304:1.63e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007114935::NZ_VIND01000001.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span448966-450901Genomic interval covered by the local TCS group.
Context group IDGCF_007114935::NZ_VIND01000001.1::G00005
Context members
FLH82_RS02180FLH82_RS02185
Partner locus tags
FLH82_RS02180FLH82_RS02185
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_012816133.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1Q8Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1Q8_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFLH82_RS02185Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VIND01000001.1Sequence record reported by the local genomic context database.
Genomic interval449 648-450 901 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span448 966-450 901 ntGCF_007114935::NZ_VIND01000001.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007114935::NZ_VIND01000001.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VIND01000001.1All displayed genes belong to this local TCS context.
Neighborhood span448 966-450 901 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
448 966 nt450 901 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FLH82_RS02180GCF_007114935#FLH82_RS02180
RROmpR

448 966-449 670 nt · Forward (+)

RefSeq WP_021426276.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293402Run 6 · HK · 360 sequences
Representative sequenceGCF_000003215#QAC_RS0207205Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293402

Simplified PFAM architecture for HKOC_2293402

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293402
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0207205

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114935
AssemblyASM711493v1 · Contighaploid
Genome composition4 309 409 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 51 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key