1 HAMP#1
4-56 aa · 53 aa · 17.4% of protein
Raw token
HAMP:4:0.000000252:56:53:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FLH41_RS15820
Histidine kinase, Classic
Clostridioides difficile · GCF_007114785
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007114785#FLH41_RS15820Stable P2CS identifier used across views.
GenomeGCF_007114785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 305 aa (74.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation3 items
2 HisKA#2
85-150 aa · 66 aa · 21.6% of protein
Raw token
HisKA:85:0.0000000641:150:66:643 HATPase_c#3
197-305 aa · 109 aa · 35.7% of protein
Raw token
HATPase_c:197:1.85e-31:305:109:109- Raw architecture: HAMP:4:0.000000252:56:53:69#HisKA:85:0.0000000641:150:66:64#HATPase_c:197:1.85e-31:305:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007114785::NZ_VIMW01000013.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span124221-125837Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_007114785::NZ_VIMW01000013.1::G00022Context members
FLH41_RS15820FLH41_RS15825
Partner locus tags
FLH41_RS15820FLH41_RS15825
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_144017156.1Primary protein accession used for annex mappings.
UniProt accessionA0ABX2GK01Primary UniProt accession resolved in the annex database.
UniProt IDA0ABX2GK01_9FIRMDisplay identifier provided by UniProt.
GO / PubMed1 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFLH41_RS15820Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VIMW01000013.1Sequence record reported by the local genomic context database.
Genomic interval124 221-125 138 nt918 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span124 221-125 837 ntGCF_007114785::NZ_VIMW01000013.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007114785::NZ_VIMW01000013.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VIMW01000013.1All displayed genes belong to this local TCS context.
Neighborhood span124 221-125 837 nt1 617 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
124 221 nt125 837 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
FLH41_RS15820GCF_007114785#FLH41_RS15820
HKClassicCurrent focus
124 221-125 138 nt · Reverse (-)
FLH41_RS15825GCF_007114785#FLH41_RS15825
RROmpR
125 145-125 837 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_007114725#FLH42_RS06525Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2882421
Simplified PFAM architecture for HKOC_2882421
PFAM domain coverage: 172 / 305 aa (56.4%)
1 aa305 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[85-148] | HATPase_c[197-304]
- Domain count: 2
- Matched identifier: HKOC_2882421
- Positioned domains: HisKA 85-148 ; HATPase_c 197-304
Cluster members and taxonomy
Representative gene: GCF_007114725#FLH42_RS06525
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114785
AssemblyASM711478v1 · Scaffoldhaploid
Genome composition4 218 668 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 52 · RR 57CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key