1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.0000000000000742:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
FLH50_RS10185
Histidine kinase, Classic
Clostridioides difficile · GCF_007114595
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_007114595#FLH50_RS10185Stable P2CS identifier used across views.
GenomeGCF_007114595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:3.91e-25:368:110:109- Raw architecture: HisKA:148:0.0000000000000742:211:64:64#HATPase_c:260:3.91e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_007114595::NZ_VIMO01000003.1::G00034
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span261446-267170Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_007114595::NZ_VIMO01000003.1::G00034Context members
FLH50_RS10185FLH50_RS10190FLH50_RS10195FLH50_RS10200FLH50_RS10205
Partner locus tags
FLH50_RS10185FLH50_RS10190FLH50_RS10195FLH50_RS10200FLH50_RS10205
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021397421.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagFLH50_RS10185Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VIMO01000003.1Sequence record reported by the local genomic context database.
Genomic interval261 446-262 561 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span261 446-267 170 ntGCF_007114595::NZ_VIMO01000003.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007114595::NZ_VIMO01000003.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VIMO01000003.1All displayed genes belong to this local TCS context.
Neighborhood span261 446-267 170 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
261 446 nt267 170 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
FLH50_RS10185GCF_007114595#FLH50_RS10185
HKClassicCurrent focus
261 446-262 561 nt · Reverse (-)
FLH50_RS10190GCF_007114595#FLH50_RS10190
RROmpR
262 597-263 295 nt · Reverse (-)
FLH50_RS10195GCF_007114595#FLH50_RS10195
RROmpR
263 676-264 356 nt · Reverse (-)
FLH50_RS10200GCF_007114595#FLH50_RS10200
HKClassic
264 406-266 421 nt · Reverse (-)
FLH50_RS10205GCF_007114595#FLH50_RS10205
RROmpR
266 493-267 170 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450145#QK3_RS16740Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2676374
Simplified PFAM architecture for HKOC_2676374
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2676374
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_000450145#QK3_RS16740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114595
AssemblyASM711459v1 · Scaffoldhaploid
Genome composition4 345 801 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 53 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key