Gene detail

FLH52_RS18690

Histidine kinase, Classic

Clostridioides difficile · GCF_007114585

ClassHKTypeClassicLength436 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007114585#FLH52_RS18690Stable P2CS identifier used across views.
GenomeGCF_007114585Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2113480Run 6 · 33 sequences · id 100% · cov 80%
External referencesWP_021408559.1 · MIST4 FLH52_RS18690RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length436 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 436 aa (36.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa436 aa
HisKA: 218-278 aa (61 aa)1HATPase_c: 334-433 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
218-278 aa · 61 aa · 14.0% of protein
Raw tokenHisKA:218:0.000000000065:278:61:64
2 HATPase_c#2
334-433 aa · 100 aa · 22.9% of protein
Raw tokenHATPase_c:334:5.22e-25:433:100:109
  • Raw architecture: HisKA:218:0.000000000065:278:61:64#HATPase_c:334:5.22e-25:433:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007114585::NZ_VIMM01000027.1::G00043
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span22952-24963Genomic interval covered by the local TCS group.
Context group IDGCF_007114585::NZ_VIMM01000027.1::G00043
Context members
FLH52_RS18685FLH52_RS18690
Partner locus tags
FLH52_RS18685FLH52_RS18690
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021408559.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFLH52_RS18690Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VIMM01000027.1Sequence record reported by the local genomic context database.
Genomic interval23 653-24 963 nt1 311 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span22 952-24 963 ntGCF_007114585::NZ_VIMM01000027.1::G00043

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007114585::NZ_VIMM01000027.1::G00043

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VIMM01000027.1All displayed genes belong to this local TCS context.
Neighborhood span22 952-24 963 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 952 nt24 963 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

FLH52_RS18685GCF_007114585#FLH52_RS18685
RROmpR

22 952-23 659 nt · Forward (+)

RefSeq WP_009890737.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2113480Run 6 · HK · 33 sequences
Representative sequenceGCF_000450785#QO7_RS13045Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2113480

Simplified PFAM architecture for HKOC_2113480

PFAM domain coverage: 166 / 436 aa (38.1%)

1 aa436 aa
HisKA: 217-278 aaHisKAHATPase_c: 330-433 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[217-278] | HATPase_c[330-433]
  • Domain count: 2
  • Matched identifier: HKOC_2113480
  • Positioned domains: HisKA 217-278 ; HATPase_c 330-433
Cluster members and taxonomy
Visualization

Representative gene: GCF_000450785#QO7_RS13045

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114585
AssemblyASM711458v1 · Contighaploid
Genome composition4 282 599 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 50 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key