Gene detail

FLH75_RS04050

Histidine kinase, CheA

Clostridioides difficile · GCF_007114185

ClassHKTypeCheALength700 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007114185#FLH75_RS04050Stable P2CS identifier used across views.
GenomeGCF_007114185Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0768910Run 6 · 342 sequences · id 100% · cov 80%
External referencesWP_021419288.1 · MIST4 FLH75_RS04050RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HptH-kinase_dimHATPase_cCheW
Protein length700 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage441 / 700 aa (63.0%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa700 aa
Hpt: 3-106 aa (104 aa)1H-kinase_dim: 312-373 aa (62 aa)2HATPase_c: 420-559 aa (140 aa)3CheW: 564-698 aa (135 aa)4
Domain-by-domain annotation4 items
1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw tokenHpt:3:0.0000000000000119:106:104:84
2 H-kinase_dim#2
312-373 aa · 62 aa · 8.9% of protein
Raw tokenH-kinase_dim:312:0.00000000000000435:373:67:67
3 HATPase_c#3
420-559 aa · 140 aa · 20.0% of protein
Raw tokenHATPase_c:420:1.77e-17:559:140:109
4 CheW#4
564-698 aa · 135 aa · 19.3% of protein
Raw tokenCheW:564:1.64e-22:698:136:138
  • Raw architecture: Hpt:3:0.0000000000000119:106:104:84#H-kinase_dim:312:0.00000000000000435:373:67:67#HATPase_c:420:1.77e-17:559:140:109#CheW:564:1.64e-22:698:136:138
  • Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_007114185::NZ_VILR01000003.1::G00036
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span40697-42799Genomic interval covered by the local TCS group.
Context group IDGCF_007114185::NZ_VILR01000003.1::G00036
Context members
FLH75_RS04050
Partner locus tags
FLH75_RS04050
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021419288.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagFLH75_RS04050Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_VILR01000003.1Sequence record reported by the local genomic context database.
Genomic interval40 697-42 799 nt2 103 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span40 697-42 799 ntGCF_007114185::NZ_VILR01000003.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007114185::NZ_VILR01000003.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_VILR01000003.1All displayed genes belong to this local TCS context.
Neighborhood span40 697-42 799 nt2 103 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 697 nt42 799 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0768910Run 6 · HK · 342 sequences
Representative sequenceGCF_000003215#QAC_RS0202765Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0768910

Simplified PFAM architecture for HKOC_0768910

PFAM domain coverage: 513 / 700 aa (73.3%)

1 aa700 aa
Hpt: 3-104 aaHptP2: 164-240 aaP2H-kinase_dim: 312-373 aaH-kinase_dimHATPase_c: 422-559 aaHATPase_cCheW: 565-698 aaCheW
HptP2H-kinase_dimHATPase_cCheW
  • Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
  • Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
  • Domain count: 5
  • Matched identifier: HKOC_0768910
  • Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202765

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007114185
AssemblyASM711418v1 · Scaffoldhaploid
Genome composition4 249 822 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key