Gene detail

EWL76_RS12875

Response regulator OmpR family

Clostridioides difficile · GCF_007002415

ClassRRTypeOmpRLength232 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002415#EWL76_RS12875Stable P2CS identifier used across views.
GenomeGCF_007002415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1119293Run 7 · 1614 sequences · id 100% · cov 80%
External referencesWP_003439430.1 · A0A0H3N2Q5 · MIST4 EWL76_RS12875RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length232 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage185 / 232 aa (79.7%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa232 aa
Response_reg: 6-115 aa (110 aa)1Trans_reg_C: 155-229 aa (75 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
6-115 aa · 110 aa · 47.4% of protein
Raw tokenResponse_reg:6:3.06e-32:115:111:111
2 Trans_reg_C#2
155-229 aa · 75 aa · 32.3% of protein
Raw tokenTrans_reg_C:155:3.4e-27:229:75:77
  • Raw architecture: Response_reg:6:3.06e-32:115:111:111#Trans_reg_C:155:3.4e-27:229:75:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007002415::NZ_SEPH01000027.1::G00026
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span19460-22894Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL76_12860RefSeq proteinWP_003439430.1
Context group IDGCF_007002415::NZ_SEPH01000027.1::G00026
Context members
EWL76_RS12870EWL76_RS12875
Partner locus tags
EWL76_RS12870EWL76_RS12875
Partner old locus tags
EWL76_12855EWL76_12860
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003439430.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2Q5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2Q5_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL76_RS12875Primary locus identifier stored in the genes table.
Old locus tagEWL76_12860Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPH01000027.1Sequence record reported by the local genomic context database.
Genomic interval22 196-22 894 nt699 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span19 460-22 894 ntGCF_007002415::NZ_SEPH01000027.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002415::NZ_SEPH01000027.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPH01000027.1All displayed genes belong to this local TCS context.
Neighborhood span19 460-22 894 nt3 435 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 460 nt22 894 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWL76_RS12870GCF_007002415#EWL76_RS12870
HKClassic

19 460-22 162 nt · Forward (+)

Old locus EWL76_12855RefSeq WP_021360608.1
EWL76_RS12875GCF_007002415#EWL76_RS12875
RROmpRCurrent focus

22 196-22 894 nt · Forward (+)

Old locus EWL76_12860RefSeq WP_003439430.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1119293Run 7 · RR · 1614 sequences
Representative sequenceGCF_000003215#QAC_RS0209450Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1119293

Simplified PFAM architecture for RROC_1119293

PFAM domain coverage: 185 / 232 aa (79.7%)

1 aa232 aa
Response_reg: 6-115 aaResponse_regResponse_reg: 6-115 aaResponse_regTrans_reg_C: 155-229 aaTrans_reg_CTrans_reg_C: 155-229 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[6-115] | Trans_reg_C[155-229]
  • Domain count: 2
  • Matched identifier: RROC_1119293
  • Positioned domains: Response_reg 6-115 ; Response_reg 6-115 ; Trans_reg_C 155-229 ; Trans_reg_C 155-229
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0209450

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002415
AssemblyASM700241v1 · Contighaploid
Genome composition4 120 629 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 45 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key