1 Response_reg#1
4-113 aa · 110 aa · 48.2% of protein
Raw token
Response_reg:4:9.43e-29:113:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL76_RS08840
Response regulator OmpR family
Clostridioides difficile · GCF_007002415
ClassRRTypeOmpRLength228 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002415#EWL76_RS08840Stable P2CS identifier used across views.
GenomeGCF_007002415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length228 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage186 / 228 aa (81.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa228 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
146-221 aa · 76 aa · 33.3% of protein
Raw token
Trans_reg_C:146:7.34e-24:221:78:77- Raw architecture: Response_reg:4:9.43e-29:113:111:111#Trans_reg_C:146:7.34e-24:221:78:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007002415::NZ_SEPH01000014.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span62836-64543Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL76_08830RefSeq proteinWP_011861401.1
Context group ID
GCF_007002415::NZ_SEPH01000014.1::G00012Context members
EWL76_RS08840EWL76_RS08845
Partner locus tags
EWL76_RS08840EWL76_RS08845
Partner old locus tags
EWL76_08830EWL76_08835
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011861401.1Primary protein accession used for annex mappings.
UniProt accessionQ187R9Primary UniProt accession resolved in the annex database.
UniProt IDQ187R9_CLOD6Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL76_RS08840Primary locus identifier stored in the genes table.
Old locus tagEWL76_08830Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPH01000014.1Sequence record reported by the local genomic context database.
Genomic interval62 836-63 522 nt687 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span62 836-64 543 ntGCF_007002415::NZ_SEPH01000014.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007002415::NZ_SEPH01000014.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPH01000014.1All displayed genes belong to this local TCS context.
Neighborhood span62 836-64 543 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
62 836 nt64 543 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL76_RS08840GCF_007002415#EWL76_RS08840
RROmpRCurrent focus
62 836-63 522 nt · Forward (+)
EWL76_RS08845GCF_007002415#EWL76_RS08845
HKClassic
63 512-64 543 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS10610Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1301544
Simplified PFAM architecture for RROC_1301544
PFAM domain coverage: 184 / 228 aa (80.7%)
1 aa228 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[4-112] | Trans_reg_C[146-220]
- Domain count: 2
- Matched identifier: RROC_1301544
- Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 146-220 ; Trans_reg_C 146-220
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS10610
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002415
AssemblyASM700241v1 · Contighaploid
Genome composition4 120 629 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 45 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key