Gene detail

EWL77_RS02000

Histidine kinase, Classic

Clostridioides difficile · GCF_007002385

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002385#EWL77_RS02000Stable P2CS identifier used across views.
GenomeGCF_007002385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550380Run 6 · 201 sequences · id 100% · cov 80%
External referencesWP_021364418.1 · MIST4 EWL77_RS02000RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-253 aa (66 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:3.62e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.000000000326:378:104:109
  • Raw architecture: HisKA_3:188:3.62e-20:253:67:68#HATPase_c:294:0.000000000326:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007002385::NZ_SEPI01000001.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span437514-439317Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL77_02000RefSeq proteinWP_021364418.1
Context group IDGCF_007002385::NZ_SEPI01000001.1::G00021
Context members
EWL77_RS02000EWL77_RS02005
Partner locus tags
EWL77_RS02000EWL77_RS02005
Partner old locus tags
EWL77_02000EWL77_02005
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021364418.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL77_RS02000Primary locus identifier stored in the genes table.
Old locus tagEWL77_02000Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPI01000001.1Sequence record reported by the local genomic context database.
Genomic interval437 514-438 677 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span437 514-439 317 ntGCF_007002385::NZ_SEPI01000001.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002385::NZ_SEPI01000001.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span437 514-439 317 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
437 514 nt439 317 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWL77_RS02000GCF_007002385#EWL77_RS02000
HKClassicCurrent focus

437 514-438 677 nt · Forward (+)

Old locus EWL77_02000RefSeq WP_021364418.1
EWL77_RS02005GCF_007002385#EWL77_RS02005
RRNarL

438 670-439 317 nt · Forward (+)

Old locus EWL77_02005RefSeq WP_009896181.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550380Run 6 · HK · 201 sequences
Representative sequenceGCF_000448745#QC1_RS06915Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550380

Simplified PFAM architecture for HKOC_2550380

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550380
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS06915

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002385
AssemblyASM700238v1 · Contighaploid
Genome composition4 138 058 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key