1 Response_reg#1
4-113 aa · 110 aa · 49.1% of protein
Raw token
Response_reg:4:1.97e-25:113:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL77_RS00605
Response regulator OmpR family
Clostridioides difficile · GCF_007002385
ClassRRTypeOmpRLength224 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002385#EWL77_RS00605Stable P2CS identifier used across views.
GenomeGCF_007002385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length224 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage184 / 224 aa (82.1%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa224 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
148-221 aa · 74 aa · 33.0% of protein
Raw token
Trans_reg_C:148:4.28e-27:221:75:77- Raw architecture: Response_reg:4:1.97e-25:113:111:111#Trans_reg_C:148:4.28e-27:221:75:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007002385::NZ_SEPI01000001.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span136253-137955Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL77_00605RefSeq proteinWP_003436727.1
Context group ID
GCF_007002385::NZ_SEPI01000001.1::G00017Context members
EWL77_RS00605EWL77_RS00610
Partner locus tags
EWL77_RS00605EWL77_RS00610
Partner old locus tags
EWL77_00605EWL77_00610
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003436727.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N1Y6Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N1Y6_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL77_RS00605Primary locus identifier stored in the genes table.
Old locus tagEWL77_00605Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPI01000001.1Sequence record reported by the local genomic context database.
Genomic interval136 253-136 927 nt675 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span136 253-137 955 ntGCF_007002385::NZ_SEPI01000001.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007002385::NZ_SEPI01000001.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPI01000001.1All displayed genes belong to this local TCS context.
Neighborhood span136 253-137 955 nt1 703 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
136 253 nt137 955 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL77_RS00605GCF_007002385#EWL77_RS00605
RROmpRCurrent focus
136 253-136 927 nt · Forward (+)
EWL77_RS00610GCF_007002385#EWL77_RS00610
HKClassic
136 951-137 955 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0207550Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1528471
Simplified PFAM architecture for RROC_1528471
PFAM domain coverage: 183 / 224 aa (81.7%)
1 aa224 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[4-112] | Trans_reg_C[149-222]
- Domain count: 2
- Matched identifier: RROC_1528471
- Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 149-222 ; Trans_reg_C 149-222
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0207550
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002385
AssemblyASM700238v1 · Contighaploid
Genome composition4 138 058 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key