Gene detail

EWL78_RS00035

Response regulator OmpR family

Clostridioides difficile · GCF_007002365

ClassRRTypeOmpRLength234 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002365#EWL78_RS00035Stable P2CS identifier used across views.
GenomeGCF_007002365Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_1047051Run 7 · 2384 sequences · id 100% · cov 80%
External referencesWP_003439080.1 · A0A0H3N8K7 · MIST4 EWL78_RS00035RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regTrans_reg_C
Protein length234 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage188 / 234 aa (80.3%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EWL78_RS00035
Domain-by-domain annotation2 items
1 Response_reg#1
7-117 aa · 111 aa · 47.4% of protein
Raw tokenResponse_reg:7:2.41e-34:117:111:111
2 Trans_reg_C#2
155-231 aa · 77 aa · 32.9% of protein
Raw tokenTrans_reg_C:155:5.71e-27:231:77:77
  • Raw architecture: Response_reg:7:2.41e-34:117:111:111#Trans_reg_C:155:5.71e-27:231:77:77
  • Domain description: 1 Response_reg,1 Trans_reg_C
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007002365::NZ_SEPJ01000001.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8844-11146Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL78_00035RefSeq proteinWP_003439080.1
Context group IDGCF_007002365::NZ_SEPJ01000001.1::G00015
Context members
EWL78_RS00030EWL78_RS00035
Partner locus tags
EWL78_RS00030EWL78_RS00035
Partner old locus tags
EWL78_00030EWL78_00035
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003439080.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N8K7Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N8K7_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL78_RS00035Primary locus identifier stored in the genes table.
Old locus tagEWL78_00035Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPJ01000001.1Sequence record reported by the local genomic context database.
Genomic interval10 442-11 146 nt705 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 844-11 146 ntGCF_007002365::NZ_SEPJ01000001.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002365::NZ_SEPJ01000001.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPJ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span8 844-11 146 nt2 303 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 844 nt11 146 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWL78_RS00030GCF_007002365#EWL78_RS00030
HKClassic

8 844-10 451 nt · Forward (+)

Old locus EWL78_00030RefSeq WP_003439079.1
EWL78_RS00035GCF_007002365#EWL78_RS00035
RROmpRCurrent focus

10 442-11 146 nt · Forward (+)

Old locus EWL78_00035RefSeq WP_003439080.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_1047051Run 7 · RR · 2384 sequences
Representative sequenceGCF_000003215#QAC_RS0202675Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.

PFAM architecture for RROC_1047051

Simplified PFAM architecture for RROC_1047051

PFAM domain coverage: 188 / 234 aa (80.3%)

1 aa234 aa
Response_reg: 7-117 aaResponse_regResponse_reg: 7-117 aaResponse_regTrans_reg_C: 155-231 aaTrans_reg_CTrans_reg_C: 155-231 aaTrans_reg_C
Response_regTrans_reg_C
  • Simplified architecture: Response_reg + Trans_reg_C
  • Raw architecture: Response_reg[7-117] | Trans_reg_C[155-231]
  • Domain count: 2
  • Matched identifier: RROC_1047051
  • Positioned domains: Response_reg 7-117 ; Response_reg 7-117 ; Trans_reg_C 155-231 ; Trans_reg_C 155-231
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202675

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002365
AssemblyASM700236v1 · Contighaploid
Genome composition4 140 034 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key