Gene detail

EWL87_RS01040

Histidine kinase, Classic

Clostridioides difficile · GCF_007002215

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_007002215#EWL87_RS01040Stable P2CS identifier used across views.
GenomeGCF_007002215Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842418Run 6 · 344 sequences · id 100% · cov 80%
External referencesWP_009893921.1 · A0A0H3NB90 · MIST4 EWL87_RS01040RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EWL87_RS01040
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000911:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:2.91e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000911:514:66:64#HATPase_c:565:2.91e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_007002215::NZ_SEPS01000001.1::G00023
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span227204-232929Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL87_01040RefSeq proteinWP_009893921.1
Context group IDGCF_007002215::NZ_SEPS01000001.1::G00023
Context members
EWL87_RS01025EWL87_RS01030EWL87_RS01035EWL87_RS01040EWL87_RS01045
Partner locus tags
EWL87_RS01025EWL87_RS01030EWL87_RS01035EWL87_RS01040EWL87_RS01045
Partner old locus tags
EWL87_01025EWL87_01030EWL87_01035EWL87_01040EWL87_01045

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893921.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NB90Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NB90_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL87_RS01040Primary locus identifier stored in the genes table.
Old locus tagEWL87_01040Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPS01000001.1Sequence record reported by the local genomic context database.
Genomic interval230 165-232 180 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span227 204-232 929 ntGCF_007002215::NZ_SEPS01000001.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002215::NZ_SEPS01000001.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPS01000001.1All displayed genes belong to this local TCS context.
Neighborhood span227 204-232 929 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
227 204 nt232 929 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

EWL87_RS01025GCF_007002215#EWL87_RS01025
HKClassic

227 204-228 319 nt · Reverse (-)

Old locus EWL87_01025RefSeq WP_009891726.1
EWL87_RS01030GCF_007002215#EWL87_RS01030
RROmpR

228 355-229 053 nt · Reverse (-)

Old locus EWL87_01030RefSeq WP_009891729.1
EWL87_RS01035GCF_007002215#EWL87_RS01035
RROmpR

229 435-230 115 nt · Reverse (-)

Old locus EWL87_01035RefSeq WP_009891737.1
EWL87_RS01040GCF_007002215#EWL87_RS01040
HKClassicCurrent focus

230 165-232 180 nt · Reverse (-)

Old locus EWL87_01040RefSeq WP_009893921.1
EWL87_RS01045GCF_007002215#EWL87_RS01045
RROmpR

232 252-232 929 nt · Reverse (-)

Old locus EWL87_01045RefSeq WP_009891739.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842418Run 6 · HK · 344 sequences
Representative sequenceGCF_000003215#QAC_RS0216530Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842418

Simplified PFAM architecture for HKOC_0842418

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842418
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216530

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002215
AssemblyASM700221v1 · Contighaploid
Genome composition4 148 060 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key