1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.00000000000008:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL89_RS01025
Histidine kinase, Classic
Clostridioides difficile · GCF_007002165
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_007002165#EWL89_RS01025Stable P2CS identifier used across views.
GenomeGCF_007002165Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:4.62e-25:368:110:109- Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_007002165::NZ_SEPU01000001.1::G00023
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span228266-233991Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL89_01025RefSeq proteinWP_009891726.1
Context group ID
GCF_007002165::NZ_SEPU01000001.1::G00023Context members
EWL89_RS01025EWL89_RS01030EWL89_RS01035EWL89_RS01040EWL89_RS01045
Partner locus tags
EWL89_RS01025EWL89_RS01030EWL89_RS01035EWL89_RS01040EWL89_RS01045
Partner old locus tags
EWL89_01025EWL89_01030EWL89_01035EWL89_01040EWL89_01045
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL89_RS01025Primary locus identifier stored in the genes table.
Old locus tagEWL89_01025Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPU01000001.1Sequence record reported by the local genomic context database.
Genomic interval228 266-229 381 nt1 116 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span228 266-233 991 ntGCF_007002165::NZ_SEPU01000001.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007002165::NZ_SEPU01000001.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPU01000001.1All displayed genes belong to this local TCS context.
Neighborhood span228 266-233 991 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
228 266 nt233 991 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
EWL89_RS01025GCF_007002165#EWL89_RS01025
HKClassicCurrent focus
228 266-229 381 nt · Reverse (-)
EWL89_RS01030GCF_007002165#EWL89_RS01030
RROmpR
229 417-230 115 nt · Reverse (-)
EWL89_RS01035GCF_007002165#EWL89_RS01035
RROmpR
230 497-231 177 nt · Reverse (-)
EWL89_RS01040GCF_007002165#EWL89_RS01040
HKClassic
231 227-233 242 nt · Reverse (-)
EWL89_RS01045GCF_007002165#EWL89_RS01045
RROmpR
233 314-233 991 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2676088
Simplified PFAM architecture for HKOC_2676088
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2676088
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0216515
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002165
AssemblyASM700216v1 · Contighaploid
Genome composition4 150 676 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key