Gene detail

EWL90_RS15850

Histidine kinase, Classic

Clostridioides difficile · GCF_007002145

ClassHKTypeClassicLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002145#EWL90_RS15850Stable P2CS identifier used across views.
GenomeGCF_007002145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2071625Run 6 · 263 sequences · id 100% · cov 80%
External referencesWP_330361571.1 · MIST4 EWL90_RS15850RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 440 aa (57.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
HAMP: 127-204 aa (78 aa)1HisKA: 216-281 aa (66 aa)2HATPase_c: 331-437 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
127-204 aa · 78 aa · 17.7% of protein
Raw tokenHAMP:127:0.00000000465:204:78:69
2 HisKA#2
216-281 aa · 66 aa · 15.0% of protein
Raw tokenHisKA:216:0.00000000125:281:66:64
3 HATPase_c#3
331-437 aa · 107 aa · 24.3% of protein
Raw tokenHATPase_c:331:1.23e-26:437:107:109
  • Raw architecture: HAMP:127:0.00000000465:204:78:69#HisKA:216:0.00000000125:281:66:64#HATPase_c:331:1.23e-26:437:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007002145::NZ_SEPV01000016.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span17283-19418Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL90_15845RefSeq proteinWP_330361571.1
Context group IDGCF_007002145::NZ_SEPV01000016.1::G00009
Context members
EWL90_RS15845EWL90_RS15850
Partner locus tags
EWL90_RS15845EWL90_RS15850
Partner old locus tags
EWL90_15840EWL90_15845
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330361571.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL90_RS15850Primary locus identifier stored in the genes table.
Old locus tagEWL90_15845Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPV01000016.1Sequence record reported by the local genomic context database.
Genomic interval18 096-19 418 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span17 283-19 418 ntGCF_007002145::NZ_SEPV01000016.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002145::NZ_SEPV01000016.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPV01000016.1All displayed genes belong to this local TCS context.
Neighborhood span17 283-19 418 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
17 283 nt19 418 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EWL90_RS15845GCF_007002145#EWL90_RS15845
RROmpR

17 283-17 975 nt · Forward (+)

Old locus EWL90_15840RefSeq WP_003434748.1
EWL90_RS15850GCF_007002145#EWL90_RS15850
HKClassicCurrent focus

18 096-19 418 nt · Forward (+)

Old locus EWL90_15845RefSeq WP_330361571.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2071625Run 6 · HK · 263 sequences
Representative sequenceGCF_000154645#UAA_RS0204430Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2071625

Simplified PFAM architecture for HKOC_2071625

PFAM domain coverage: 223 / 440 aa (50.7%)

1 aa440 aa
HAMP: 154-204 aaHAMPHisKA: 217-281 aaHisKAHATPase_c: 331-437 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[154-204] | HisKA[217-281] | HATPase_c[331-437]
  • Domain count: 3
  • Matched identifier: HKOC_2071625
  • Positioned domains: HAMP 154-204 ; HisKA 217-281 ; HATPase_c 331-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154645#UAA_RS0204430

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002145
AssemblyASM700214v1 · Contighaploid
Genome composition4 147 090 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key