1 Response_reg#1
5-109 aa · 105 aa · 43.6% of protein
Raw token
Response_reg:5:1.86e-28:109:106:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL90_RS00540
Response regulator OmpR family
Clostridioides difficile · GCF_007002145
ClassRRTypeOmpRLength241 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002145#EWL90_RS00540Stable P2CS identifier used across views.
GenomeGCF_007002145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length241 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage182 / 241 aa (75.5%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa241 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
160-236 aa · 77 aa · 32.0% of protein
Raw token
Trans_reg_C:160:3.22e-32:236:77:77- Raw architecture: Response_reg:5:1.86e-28:109:106:111#Trans_reg_C:160:3.22e-32:236:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007002145::NZ_SEPV01000001.1::G00022
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span124107-126239Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL90_00540RefSeq proteinWP_009893221.1
Context group ID
GCF_007002145::NZ_SEPV01000001.1::G00022Context members
EWL90_RS00540EWL90_RS00545
Partner locus tags
EWL90_RS00540EWL90_RS00545
Partner old locus tags
EWL90_00540EWL90_00545
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009893221.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N751Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N751_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL90_RS00540Primary locus identifier stored in the genes table.
Old locus tagEWL90_00540Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPV01000001.1Sequence record reported by the local genomic context database.
Genomic interval124 107-124 832 nt726 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span124 107-126 239 ntGCF_007002145::NZ_SEPV01000001.1::G00022
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007002145::NZ_SEPV01000001.1::G00022Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPV01000001.1All displayed genes belong to this local TCS context.
Neighborhood span124 107-126 239 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
124 107 nt126 239 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL90_RS00540GCF_007002145#EWL90_RS00540
RROmpRCurrent focus
124 107-124 832 nt · Forward (+)
EWL90_RS00545GCF_007002145#EWL90_RS00545
HKClassic
124 836-126 239 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0208645Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0862557
Simplified PFAM architecture for RROC_0862557
PFAM domain coverage: 184 / 241 aa (76.3%)
1 aa241 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[5-111] | Trans_reg_C[160-236]
- Domain count: 2
- Matched identifier: RROC_0862557
- Positioned domains: Response_reg 5-111 ; Response_reg 5-111 ; Trans_reg_C 160-236 ; Trans_reg_C 160-236
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0208645
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002145
AssemblyASM700214v1 · Contighaploid
Genome composition4 147 090 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key