1 HisKA#1
207-272 aa · 66 aa · 15.3% of protein
Raw token
HisKA:207:0.000000000000018:272:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL92_RS07175
Histidine kinase, Classic
Clostridioides difficile · GCF_007002095
ClassHKTypeClassicLength430 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007002095#EWL92_RS07175Stable P2CS identifier used across views.
GenomeGCF_007002095Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length430 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage177 / 430 aa (41.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa430 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
320-430 aa · 111 aa · 25.8% of protein
Raw token
HATPase_c:320:1.05e-29:430:111:109- Raw architecture: HisKA:207:0.000000000000018:272:66:64#HATPase_c:320:1.05e-29:430:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007002095::NZ_SEPX01000004.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span252660-254632Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL92_07175RefSeq proteinWP_074034324.1
Context group ID
GCF_007002095::NZ_SEPX01000004.1::G00044Context members
EWL92_RS07175EWL92_RS07180
Partner locus tags
EWL92_RS07175EWL92_RS07180
Partner old locus tags
EWL92_07175EWL92_07180
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_074034324.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL92_RS07175Primary locus identifier stored in the genes table.
Old locus tagEWL92_07175Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEPX01000004.1Sequence record reported by the local genomic context database.
Genomic interval252 660-253 952 nt1 293 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span252 660-254 632 ntGCF_007002095::NZ_SEPX01000004.1::G00044
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007002095::NZ_SEPX01000004.1::G00044Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEPX01000004.1All displayed genes belong to this local TCS context.
Neighborhood span252 660-254 632 nt1 973 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
252 660 nt254 632 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL92_RS07175GCF_007002095#EWL92_RS07175
HKClassicCurrent focus
252 660-253 952 nt · Reverse (-)
EWL92_RS07180GCF_007002095#EWL92_RS07180
RROmpR
253 946-254 632 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003433755#DW120_RS20540Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2173814
Simplified PFAM architecture for HKOC_2173814
PFAM domain coverage: 174 / 430 aa (40.5%)
1 aa430 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[208-272] | HATPase_c[321-429]
- Domain count: 2
- Matched identifier: HKOC_2173814
- Positioned domains: HisKA 208-272 ; HATPase_c 321-429
Cluster members and taxonomy
Representative gene: GCF_003433755#DW120_RS20540
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002095
AssemblyASM700209v1 · Contighaploid
Genome composition4 187 773 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key