Gene detail

EWL93_RS11530

Histidine kinase, Classic

Clostridioides difficile · GCF_007002065

Open genome Open selected cluster RefSeq

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextorphan

Gene IDGCF_007002065#EWL93_RS11530Stable P2CS identifier used across views.

GenomeGCF_007002065Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides

Selected clusterHKOC_1752187Run 6 · 26 sequences · id 100% · cov 80%

External referencesWP_021423424.1 · MIST4 EWL93_RS11530RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c

Protein length450 aaLength used to scale native and Biotite-like views.

Annotated domains22 with usable coordinates.

Domain coverage176 / 450 aa (39.1%)Merged over positioned domains only.

Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.

Signal peptideUnavailableNo TMPRED prediction file matched this gene.

Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.

Complete domain annotations

Domain view

Native Biotite-like

Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.

1 aa450 aa

Domain-by-domain annotation2 items

1 HisKA#1

228-296 aa · 69 aa · 15.3% of protein

Raw tokenHisKA:228:0.000000000000216:296:69:64

2 HATPase_c#2

343-449 aa · 107 aa · 23.8% of protein

Raw tokenHATPase_c:343:1.56e-27:449:108:109

Raw architecture: HisKA:228:0.000000000000216:296:69:64#HATPase_c:343:1.56e-27:449:108:109
Domain description: 1 HisKA,1 HATPase_c
TM description: N/A
TMPRED source: No TMPRED file loaded
TMPRED segments: N/A
Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_007002065::NZ_SEPY01000024.1::G00020

Group size11 locus tag listed below.

HK / RR1 / 0Counts resolved for the local TCS neighborhood.

Context span39421-40773Genomic interval covered by the local TCS group.

Identifiers

Old locus tagEWL93_11525RefSeq proteinWP_021423424.1

Context group IDGCF_007002065::NZ_SEPY01000024.1::G00020

Context members

EWL93_RS11530

Partner locus tags

EWL93_RS11530

Partner old locus tags

EWL93_11525

Partner protein IDs

WP_021423424.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021423424.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWL93_RS11530Primary locus identifier stored in the genes table.

Old locus tagEWL93_11525Legacy locus tag recovered from the local context mapping.

Contig / repliconNZ_SEPY01000024.1Sequence record reported by the local genomic context database.

Genomic interval39 421-40 773 nt1 353 nt · Forward (+)

StrandForward (+)Strand sign follows the local context database convention.

Local TCS group span39 421-40 773 ntGCF_007002065::NZ_SEPY01000024.1::G00020

Quick actions

Open genome Search genes in genome

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007002065::NZ_SEPY01000024.1::G00020

Graphic view

Compact Biotite-like

Zoom

Full window Focus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.

Contig / repliconNZ_SEPY01000024.1All displayed genes belong to this local TCS context.

Neighborhood span39 421-40 773 nt1 353 nt

Members11 current focus gene

Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.

39 421 nt40 773 nt

+-EWL93_RS11530

Neighborhood gene cards

1 gene in the current local neighborhood.

EWL93_RS11530GCF_007002065#EWL93_RS11530

HKClassicCurrent focus

39 421-40 773 nt · Forward (+)

Old locus EWL93_11525RefSeq WP_021423424.1

Open current gene

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster

HKOC_1752187HK

Run 626 sequencesid 100%cov 80%

PFAM HisKA + HATPase_c

Representative GCF_007002025#EWL95_RS13645

Selected clusterHKOC_1752187Run 6 · HK · 26 sequences

Representative sequenceGCF_007002025#EWL95_RS13645Use this link to inspect the representative gene detail.

PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

Open in cluster search Open representative gene

PFAM architecture for HKOC_1752187

Simplified PFAM architecture for HKOC_1752187

PFAM domain coverage: 167 / 467 aa (35.8%)

1 aa467 aa

HisKAHATPase_c

Simplified architecture: HisKA + HATPase_c
Raw architecture: HisKA[245-306] | HATPase_c[362-466]
Domain count: 2
Matched identifier: HKOC_1752187
Positioned domains: HisKA 245-306 ; HATPase_c 362-466

Cluster members and taxonomy

Representative gene: GCF_007002025#EWL95_RS13645

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007002065

AssemblyASM700206v1 · Contighaploid

Genome composition4 204 994 bp · 29,0% GCClostridioides difficile

Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0

Ranked taxonomy7 ranked levels available

SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides

Lineage path7 lineage nodes

1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Open genome Search genes in genome Search HK genes NCBI assembly files

Related genes

Preview from the same derived genome key