1 HisKA#1
82-144 aa · 63 aa · 20.9% of protein
Raw token
HisKA:82:0.000000074:144:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL99_RS09290
Histidine kinase, Classic
Clostridioides difficile · GCF_007001985
ClassHKTypeClassicLength302 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001985#EWL99_RS09290Stable P2CS identifier used across views.
GenomeGCF_007001985Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length302 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 302 aa (54.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa302 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
196-295 aa · 100 aa · 33.1% of protein
Raw token
HATPase_c:196:2.14e-22:295:100:109- Raw architecture: HisKA:82:0.000000074:144:63:64#HATPase_c:196:2.14e-22:295:100:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001985::NZ_SEQE01000014.1::G00006
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span65444-67025Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL99_09280RefSeq proteinWP_016729031.1
Context group ID
GCF_007001985::NZ_SEQE01000014.1::G00006Context members
EWL99_RS09285EWL99_RS09290
Partner locus tags
EWL99_RS09285EWL99_RS09290
Partner old locus tags
EWL99_09275EWL99_09280
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_016729031.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL99_RS09290Primary locus identifier stored in the genes table.
Old locus tagEWL99_09280Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQE01000014.1Sequence record reported by the local genomic context database.
Genomic interval66 117-67 025 nt909 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span65 444-67 025 ntGCF_007001985::NZ_SEQE01000014.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001985::NZ_SEQE01000014.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQE01000014.1All displayed genes belong to this local TCS context.
Neighborhood span65 444-67 025 nt1 582 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
65 444 nt67 025 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL99_RS09285GCF_007001985#EWL99_RS09285
RROmpR
65 444-66 115 nt · Forward (+)
EWL99_RS09290GCF_007001985#EWL99_RS09290
HKClassicCurrent focus
66 117-67 025 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_034188235#SQ514_RS09400Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2883605
Simplified PFAM architecture for HKOC_2883605
PFAM domain coverage: 165 / 304 aa (54.3%)
1 aa304 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[84-146] | HATPase_c[197-298]
- Domain count: 2
- Matched identifier: HKOC_2883605
- Positioned domains: HisKA 84-146 ; HATPase_c 197-298
Cluster members and taxonomy
Representative gene: GCF_034188235#SQ514_RS09400
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001985
AssemblyASM700198v1 · Contighaploid
Genome composition4 247 042 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key