1 Response_reg#1
4-112 aa · 109 aa · 47.4% of protein
Raw token
Response_reg:4:6.96e-33:112:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWL99_RS05340
Response regulator OmpR family
Clostridioides difficile · GCF_007001985
ClassRRTypeOmpRLength230 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001985#EWL99_RS05340Stable P2CS identifier used across views.
GenomeGCF_007001985Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length230 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage186 / 230 aa (80.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa230 aa
Domain-by-domain annotation2 items
2 Trans_reg_C#2
151-227 aa · 77 aa · 33.5% of protein
Raw token
Trans_reg_C:151:3.95e-28:227:77:77- Raw architecture: Response_reg:4:6.96e-33:112:111:111#Trans_reg_C:151:3.95e-28:227:77:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001985::NZ_SEQE01000007.1::G00052
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span58960-61095Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWL99_05330RefSeq proteinWP_003434748.1
Context group ID
GCF_007001985::NZ_SEQE01000007.1::G00052Context members
EWL99_RS05340EWL99_RS05345
Partner locus tags
EWL99_RS05340EWL99_RS05345
Partner old locus tags
EWL99_05330EWL99_05335
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003434748.1Primary protein accession used for annex mappings.
UniProt accessionQ188S4Primary UniProt accession resolved in the annex database.
UniProt IDQ188S4_CLOD6Display identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWL99_RS05340Primary locus identifier stored in the genes table.
Old locus tagEWL99_05330Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQE01000007.1Sequence record reported by the local genomic context database.
Genomic interval58 960-59 652 nt693 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span58 960-61 095 ntGCF_007001985::NZ_SEQE01000007.1::G00052
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001985::NZ_SEQE01000007.1::G00052Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQE01000007.1All displayed genes belong to this local TCS context.
Neighborhood span58 960-61 095 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
58 960 nt61 095 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWL99_RS05340GCF_007001985#EWL99_RS05340
RROmpRCurrent focus
58 960-59 652 nt · Forward (+)
EWL99_RS05345GCF_007001985#EWL99_RS05345
HKClassic
59 671-61 095 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0202550Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_1199614
Simplified PFAM architecture for RROC_1199614
PFAM domain coverage: 185 / 230 aa (80.4%)
1 aa230 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[4-112] | Trans_reg_C[151-226]
- Domain count: 2
- Matched identifier: RROC_1199614
- Positioned domains: Response_reg 4-112 ; Response_reg 4-112 ; Trans_reg_C 151-226 ; Trans_reg_C 151-226
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0202550
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001985
AssemblyASM700198v1 · Contighaploid
Genome composition4 247 042 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key