Gene detail

EWM04_RS08935

Histidine kinase, Classic

Clostridioides difficile · GCF_007001845

ClassHKTypeClassicLength385 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007001845#EWM04_RS08935Stable P2CS identifier used across views.
GenomeGCF_007001845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2567055Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_021392387.1 · MIST4 EWM04_RS08935RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length385 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 385 aa (45.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa385 aa
HisKA: 163-231 aa (69 aa)1HATPase_c: 278-384 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
163-231 aa · 69 aa · 17.9% of protein
Raw tokenHisKA:163:0.000000000000113:231:69:64
2 HATPase_c#2
278-384 aa · 107 aa · 27.8% of protein
Raw tokenHATPase_c:278:6.49e-28:384:108:109
  • Raw architecture: HisKA:163:0.000000000000113:231:69:64#HATPase_c:278:6.49e-28:384:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_007001845::NZ_SEQJ01000004.1::G00031
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span155758-156915Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM04_08935RefSeq proteinWP_021392387.1
Context group IDGCF_007001845::NZ_SEQJ01000004.1::G00031
Context members
EWM04_RS08935
Partner locus tags
EWM04_RS08935
Partner old locus tags
EWM04_08935
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021392387.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEWM04_RS08935Primary locus identifier stored in the genes table.
Old locus tagEWM04_08935Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQJ01000004.1Sequence record reported by the local genomic context database.
Genomic interval155 758-156 915 nt1 158 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span155 758-156 915 ntGCF_007001845::NZ_SEQJ01000004.1::G00031

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001845::NZ_SEQJ01000004.1::G00031

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQJ01000004.1All displayed genes belong to this local TCS context.
Neighborhood span155 758-156 915 nt1 158 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
155 758 nt156 915 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

EWM04_RS08935GCF_007001845#EWM04_RS08935
HKClassicCurrent focus

155 758-156 915 nt · Forward (+)

Old locus EWM04_08935RefSeq WP_021392387.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2567055Run 6 · HK · 4 sequences
Representative sequenceGCF_007001845#EWM04_RS08935The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2567055

Simplified PFAM architecture for HKOC_2567055

PFAM domain coverage: 167 / 385 aa (43.4%)

1 aa385 aa
HisKA: 163-224 aaHisKAHATPase_c: 280-384 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[163-224] | HATPase_c[280-384]
  • Domain count: 2
  • Matched identifier: HKOC_2567055
  • Positioned domains: HisKA 163-224 ; HATPase_c 280-384
Cluster members and taxonomy
Visualization

Representative gene: GCF_007001845#EWM04_RS08935

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001845
AssemblyASM700184v1 · Contighaploid
Genome composition4 265 563 bp · 28,0% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 47 · RR 53CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key