1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw token
HisKA:124:0.000000297:189:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM13_RS02865
Histidine kinase, Classic
Clostridioides difficile · GCF_007001665
ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001665#EWM13_RS02865Stable P2CS identifier used across views.
GenomeGCF_007001665Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw token
HATPase_c:241:2.93e-24:341:101:109- Raw architecture: HisKA:124:0.000000297:189:66:64#HATPase_c:241:2.93e-24:341:101:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001665::NZ_SEQS01000003.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span27358-29065Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM13_02865RefSeq proteinWP_021369088.1
Context group ID
GCF_007001665::NZ_SEQS01000003.1::G00034Context members
EWM13_RS02865EWM13_RS02870
Partner locus tags
EWM13_RS02865EWM13_RS02870
Partner old locus tags
EWM13_02865EWM13_02870
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021369088.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3H3E0Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3H3E0_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM13_RS02865Primary locus identifier stored in the genes table.
Old locus tagEWM13_02865Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQS01000003.1Sequence record reported by the local genomic context database.
Genomic interval27 358-28 389 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span27 358-29 065 ntGCF_007001665::NZ_SEQS01000003.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001665::NZ_SEQS01000003.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQS01000003.1All displayed genes belong to this local TCS context.
Neighborhood span27 358-29 065 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
27 358 nt29 065 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWM13_RS02865GCF_007001665#EWM13_RS02865
HKClassicCurrent focus
27 358-28 389 nt · Reverse (-)
EWM13_RS02870GCF_007001665#EWM13_RS02870
RROmpR
28 379-29 065 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000235905#HMPREF9945_RS14125Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2827842
Simplified PFAM architecture for HKOC_2827842
PFAM domain coverage: 173 / 343 aa (50.4%)
1 aa343 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[124-189] | HATPase_c[236-342]
- Domain count: 2
- Matched identifier: HKOC_2827842
- Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Representative gene: GCF_000235905#HMPREF9945_RS14125
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001665
AssemblyASM700166v1 · Contighaploid
Genome composition4 055 225 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key