1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw token
HAMP:166:0.00000407:232:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM39_RS02125
Histidine kinase, Classic
Clostridioides difficile · GCF_007001595
ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001595#EWM39_RS02125Stable P2CS identifier used across views.
GenomeGCF_007001595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
Domain-by-domain annotation3 items
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw token
HisKA:245:0.0000000000000209:312:68:643 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw token
HATPase_c:359:4.32e-26:465:108:109- Raw architecture: HAMP:166:0.00000407:232:69:69#HisKA:245:0.0000000000000209:312:68:64#HATPase_c:359:4.32e-26:465:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001595::NZ_SEQW01000002.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span47248-49380Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM39_02125RefSeq proteinWP_142793537.1
Context group ID
GCF_007001595::NZ_SEQW01000002.1::G00029Context members
EWM39_RS02125EWM39_RS02130
Partner locus tags
EWM39_RS02125EWM39_RS02130
Partner old locus tags
EWM39_02125EWM39_02130
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_142793537.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM39_RS02125Primary locus identifier stored in the genes table.
Old locus tagEWM39_02125Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SEQW01000002.1Sequence record reported by the local genomic context database.
Genomic interval47 248-48 651 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span47 248-49 380 ntGCF_007001595::NZ_SEQW01000002.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001595::NZ_SEQW01000002.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SEQW01000002.1All displayed genes belong to this local TCS context.
Neighborhood span47 248-49 380 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
47 248 nt49 380 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWM39_RS02125GCF_007001595#EWM39_RS02125
HKClassicCurrent focus
47 248-48 651 nt · Reverse (-)
EWM39_RS02130GCF_007001595#EWM39_RS02130
RROmpR
48 655-49 380 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_007001495#EWM44_RS07695Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1752186
Simplified PFAM architecture for HKOC_1752186
PFAM domain coverage: 172 / 467 aa (36.8%)
1 aa467 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-309] | HATPase_c[359-465]
- Domain count: 2
- Matched identifier: HKOC_1752186
- Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Representative gene: GCF_007001495#EWM44_RS07695
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001595
AssemblyASM700159v1 · Contighaploid
Genome composition4 360 576 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key