1 HisKA#1
85-154 aa · 70 aa · 23.0% of protein
Raw token
HisKA:85:0.00000000000133:154:70:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM43_RS16075
Histidine kinase, Classic
Clostridioides difficile · GCF_007001505
ClassHKTypeClassicLength305 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001505#EWM43_RS16075Stable P2CS identifier used across views.
GenomeGCF_007001505Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length305 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 305 aa (57.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa305 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
201-304 aa · 104 aa · 34.1% of protein
Raw token
HATPase_c:201:6.27e-28:304:106:109- Raw architecture: HisKA:85:0.00000000000133:154:70:64#HATPase_c:201:6.27e-28:304:106:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001505::NZ_SERA01000030.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5604-7210Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM43_16070RefSeq proteinWP_021365109.1
Context group ID
GCF_007001505::NZ_SERA01000030.1::G00028Context members
EWM43_RS16070EWM43_RS16075
Partner locus tags
EWM43_RS16070EWM43_RS16075
Partner old locus tags
EWM43_16065EWM43_16070
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021365109.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM43_RS16075Primary locus identifier stored in the genes table.
Old locus tagEWM43_16070Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERA01000030.1Sequence record reported by the local genomic context database.
Genomic interval6 293-7 210 nt918 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 604-7 210 ntGCF_007001505::NZ_SERA01000030.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001505::NZ_SERA01000030.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERA01000030.1All displayed genes belong to this local TCS context.
Neighborhood span5 604-7 210 nt1 607 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 604 nt7 210 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWM43_RS16070GCF_007001505#EWM43_RS16070
RROmpR
5 604-6 293 nt · Forward (+)
EWM43_RS16075GCF_007001505#EWM43_RS16075
HKClassicCurrent focus
6 293-7 210 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_900166185#B2B97_RS03305Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2881211
Simplified PFAM architecture for HKOC_2881211
PFAM domain coverage: 171 / 307 aa (55.7%)
1 aa307 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[90-156] | HATPase_c[203-306]
- Domain count: 2
- Matched identifier: HKOC_2881211
- Positioned domains: HisKA 90-156 ; HATPase_c 203-306
Cluster members and taxonomy
Representative gene: GCF_900166185#B2B97_RS03305
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001505
AssemblyASM700150v1 · Contighaploid
Genome composition4 364 073 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key