1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw token
HisKA:457:0.0000000000000203:524:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EWM43_RS01085
Histidine kinase, Classic
Clostridioides difficile · GCF_007001505
ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001505#EWM43_RS01085Stable P2CS identifier used across views.
GenomeGCF_007001505Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw token
HATPase_c:570:0.00000000000196:663:98:109- Raw architecture: HisKA:457:0.0000000000000203:524:68:64#HATPase_c:570:0.00000000000196:663:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_007001505::NZ_SERA01000001.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span248479-251427Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEWM43_01085RefSeq proteinWP_009897457.1
Context group ID
GCF_007001505::NZ_SERA01000001.1::G00018Context members
EWM43_RS01085EWM43_RS01095
Partner locus tags
EWM43_RS01085EWM43_RS01095
Partner old locus tags
EWM43_01085EWM43_01095
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009897457.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74Q9S7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74Q9S7_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEWM43_RS01085Primary locus identifier stored in the genes table.
Old locus tagEWM43_01085Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_SERA01000001.1Sequence record reported by the local genomic context database.
Genomic interval248 479-250 539 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span248 479-251 427 ntGCF_007001505::NZ_SERA01000001.1::G00018
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_007001505::NZ_SERA01000001.1::G00018Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_SERA01000001.1All displayed genes belong to this local TCS context.
Neighborhood span248 479-251 427 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
248 479 nt251 427 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EWM43_RS01085GCF_007001505#EWM43_RS01085
HKClassicCurrent focus
248 479-250 539 nt · Reverse (-)
EWM43_RS01095GCF_007001505#EWM43_RS01095
RROmpR
250 735-251 427 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS12360Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0800915
Simplified PFAM architecture for HKOC_0800915
PFAM domain coverage: 160 / 686 aa (23.3%)
1 aa686 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[457-524] | HATPase_c[571-662]
- Domain count: 2
- Matched identifier: HKOC_0800915
- Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS12360
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001505
AssemblyASM700150v1 · Contighaploid
Genome composition4 364 073 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key