Gene detail

D1N53_RS16045

Histidine kinase, Classic

Clostridioides difficile · GCF_007001255

ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001255#D1N53_RS16045Stable P2CS identifier used across views.
GenomeGCF_007001255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2641472Run 6 · 374 sequences · id 100% · cov 80%
External referencesWP_009903643.1 · A0AB74QFB2 · MIST4 D1N53_RS16045RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 376 aa (65.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa376 aa
HAMP: 62-131 aa (70 aa)1HisKA: 156-221 aa (66 aa)2HATPase_c: 267-376 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw tokenHAMP:62:0.0000000000123:131:70:69
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw tokenHisKA:156:0.00000000000000435:221:66:64
3 HATPase_c#3
267-376 aa · 110 aa · 29.3% of protein
Raw tokenHATPase_c:267:7.88e-18:376:111:109
  • Raw architecture: HAMP:62:0.0000000000123:131:70:69#HisKA:156:0.00000000000000435:221:66:64#HATPase_c:267:7.88e-18:376:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007001255::NZ_QWVH01000108.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4694-6492Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N53_16055RefSeq proteinWP_009903643.1
Context group IDGCF_007001255::NZ_QWVH01000108.1::G00002
Context members
D1N53_RS16045D1N53_RS16050
Partner locus tags
D1N53_RS16045D1N53_RS16050
Partner old locus tags
D1N53_16055D1N53_16060
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009903643.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QFB2Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QFB2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N53_RS16045Primary locus identifier stored in the genes table.
Old locus tagD1N53_16055Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVH01000108.1Sequence record reported by the local genomic context database.
Genomic interval4 694-5 824 nt1 131 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 694-6 492 ntGCF_007001255::NZ_QWVH01000108.1::G00002

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001255::NZ_QWVH01000108.1::G00002

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVH01000108.1All displayed genes belong to this local TCS context.
Neighborhood span4 694-6 492 nt1 799 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 694 nt6 492 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N53_RS16045GCF_007001255#D1N53_RS16045
HKClassicCurrent focus

4 694-5 824 nt · Reverse (-)

Old locus D1N53_16055RefSeq WP_009903643.1
D1N53_RS16050GCF_007001255#D1N53_RS16050
RROmpR

5 821-6 492 nt · Reverse (-)

Old locus D1N53_16060RefSeq WP_009898333.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2641472Run 6 · HK · 374 sequences
Representative sequenceGCF_000155025#UAB_RS0217365Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2641472

Simplified PFAM architecture for HKOC_2641472

PFAM domain coverage: 227 / 376 aa (60.4%)

1 aa376 aa
HAMP: 79-131 aaHAMPHisKA: 156-221 aaHisKAHATPase_c: 268-375 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[79-131] | HisKA[156-221] | HATPase_c[268-375]
  • Domain count: 3
  • Matched identifier: HKOC_2641472
  • Positioned domains: HAMP 79-131 ; HisKA 156-221 ; HATPase_c 268-375
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0217365

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001255
AssemblyASM700125v1 · Contighaploid
Genome composition4 498 869 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 50 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key