Gene detail

D1N53_RS14170

Histidine kinase, Classic

Clostridioides difficile · GCF_007001255

ClassHKTypeClassicLength469 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001255#D1N53_RS14170Stable P2CS identifier used across views.
GenomeGCF_007001255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1727354Run 6 · 50 sequences · id 100% · cov 80%
External referencesWP_021422393.1 · MIST4 D1N53_RS14170RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length469 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage304 / 469 aa (64.8%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa469 aa
H_kinase_N: 12-142 aa (131 aa)1HisKA_2: 276-350 aa (75 aa)2HATPase_c: 370-467 aa (98 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
12-142 aa · 131 aa · 27.9% of protein
Raw tokenH_kinase_N:12:1.36e-36:142:132:139
2 HisKA_2#2
276-350 aa · 75 aa · 16.0% of protein
Raw tokenHisKA_2:276:2.59e-16:350:76:76
3 HATPase_c#3
370-467 aa · 98 aa · 20.9% of protein
Raw tokenHATPase_c:370:0.0000000713:467:114:109
  • Raw architecture: H_kinase_N:12:1.36e-36:142:132:139#HisKA_2:276:2.59e-16:350:76:76#HATPase_c:370:0.0000000713:467:114:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007001255::NZ_QWVH01000081.1::G00059
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4978-6955Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N53_14180RefSeq proteinWP_021422393.1
Context group IDGCF_007001255::NZ_QWVH01000081.1::G00059
Context members
D1N53_RS14165D1N53_RS14170
Partner locus tags
D1N53_RS14165D1N53_RS14170
Partner old locus tags
D1N53_14175D1N53_14180
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021422393.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N53_RS14170Primary locus identifier stored in the genes table.
Old locus tagD1N53_14180Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVH01000081.1Sequence record reported by the local genomic context database.
Genomic interval5 546-6 955 nt1 410 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 978-6 955 ntGCF_007001255::NZ_QWVH01000081.1::G00059

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001255::NZ_QWVH01000081.1::G00059

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVH01000081.1All displayed genes belong to this local TCS context.
Neighborhood span4 978-6 955 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 978 nt6 955 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N53_RS14165GCF_007001255#D1N53_RS14165
RRAmiR_NasR

4 978-5 553 nt · Forward (+)

Old locus D1N53_14175RefSeq WP_003423977.1
D1N53_RS14170GCF_007001255#D1N53_RS14170
HKClassicCurrent focus

5 546-6 955 nt · Forward (+)

Old locus D1N53_14180RefSeq WP_021422393.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1727354Run 6 · HK · 50 sequences
Representative sequenceGCF_000451765#QSM_RS08830Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1727354

Simplified PFAM architecture for HKOC_1727354

PFAM domain coverage: 302 / 469 aa (64.4%)

1 aa469 aa
GAF_PdtaS: 6-141 aaGAF_PdtaSHisKA_2: 276-347 aaHisKA_2HATPase_c: 373-466 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[6-141] | HisKA_2[276-347] | HATPase_c[373-466]
  • Domain count: 3
  • Matched identifier: HKOC_1727354
  • Positioned domains: GAF_PdtaS 6-141 ; HisKA_2 276-347 ; HATPase_c 373-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451765#QSM_RS08830

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 50 total members. Page 1 / 1.

GCF_000451765#QSM_RS08830 (representative)
QSM_RS08830 · HK · Classic
RefSeq: WP_021422393.1
GCF_000451865#QU3_RS09855
QU3_RS09855 · HK · Classic
RefSeq: WP_021422393.1
GCF_000821005#TY67_RS04830
TY67_RS04830 · HK · Classic
RefSeq: WP_021422393.1
GCF_002300845#BGT94_RS07215
BGT94_RS07215 · HK · Classic
RefSeq: WP_021422393.1
GCF_002301735#BGU40_RS09070
BGU40_RS09070 · HK · Classic
RefSeq: WP_021422393.1
GCF_004313765#E0N69_RS07865
E0N69_RS07865 · HK · Classic
RefSeq: WP_021422393.1
GCF_004313965#E0N81_RS13650
E0N81_RS13650 · HK · Classic
RefSeq: WP_021422393.1
GCF_004313985#E0N77_RS15915
E0N77_RS15915 · HK · Classic
RefSeq: WP_021422393.1
GCF_004315845#E0P96_RS11130
E0P96_RS11130 · HK · Classic
RefSeq: WP_021422393.1
GCF_004316345#E0P93_RS15635
E0P93_RS15635 · HK · Classic
RefSeq: WP_021422393.1
GCF_007001225#D1N54_RS04405
D1N54_RS04405 · HK · Classic
RefSeq: WP_021422393.1
GCF_007001255#D1N53_RS14170
D1N53_RS14170 · HK · Classic
RefSeq: WP_021422393.1
GCF_007001275#D1N52_RS08990
D1N52_RS08990 · HK · Classic
RefSeq: WP_021422393.1
GCF_007001285#D1N51_RS11545
D1N51_RS11545 · HK · Classic
RefSeq: WP_021422393.1
GCF_007113935#FLH86_RS04145
FLH86_RS04145 · HK · Classic
RefSeq: WP_021422393.1
GCF_007113975#FLH85_RS04145
FLH85_RS04145 · HK · Classic
RefSeq: WP_021422393.1
GCF_007114005#FLH84_RS04765
FLH84_RS04765 · HK · Classic
RefSeq: WP_021422393.1
GCF_007114015#FLH83_RS04145
FLH83_RS04145 · HK · Classic
RefSeq: WP_021422393.1
GCF_007114595#FLH50_RS04190
FLH50_RS04190 · HK · Classic
RefSeq: WP_021422393.1
GCF_007114645#FLH48_RS02445
FLH48_RS02445 · HK · Classic
RefSeq: WP_021422393.1
GCF_011881455#GSQ29_RS12765
GSQ29_RS12765 · HK · Classic
RefSeq: WP_021422393.1
GCF_012102905#GSQ40_RS14605
GSQ40_RS14605 · HK · Classic
RefSeq: WP_021422393.1
GCF_018264045#E1H42_RS08760
E1H42_RS08760 · HK · Classic
RefSeq: WP_021422393.1
GCF_025532535#H3U07_RS00860
H3U07_RS00860 · HK · Classic
RefSeq: WP_021422393.1
GCF_025532655#H3U00_RS03310
H3U00_RS03310 · HK · Classic
RefSeq: WP_021422393.1
GCF_025532955#H3U18_RS03315
H3U18_RS03315 · HK · Classic
RefSeq: WP_021422393.1
GCF_025533195#H3U30_RS00865
H3U30_RS00865 · HK · Classic
RefSeq: WP_021422393.1
GCF_030251085#QQO34_RS08375
QQO34_RS08375 · HK · Classic
RefSeq: WP_021422393.1
GCF_034188105#SQ932_RS10260
SQ932_RS10260 · HK · Classic
RefSeq: WP_021422393.1
GCF_034188335#SQ509_RS06320
SQ509_RS06320 · HK · Classic
RefSeq: WP_021422393.1
GCF_034188425#SRB89_RS01985
SRB89_RS01985 · HK · Classic
RefSeq: WP_021422393.1
GCF_034188745#SQ904_RS13125
SQ904_RS13125 · HK · Classic
RefSeq: WP_021422393.1
GCF_034188865#SRC83_RS04125
SRC83_RS04125 · HK · Classic
RefSeq: WP_021422393.1
GCF_036442095#V3P90_RS03275
V3P90_RS03275 · HK · Classic
RefSeq: WP_021422393.1
GCF_036698135#LFB35_RS02350
LFB35_RS02350 · HK · Classic
RefSeq: WP_021422393.1
GCF_036698495#LFB05_RS02380
LFB05_RS02380 · HK · Classic
RefSeq: WP_021422393.1
GCF_036698835#LE578_RS00860
LE578_RS00860 · HK · Classic
RefSeq: WP_021422393.1
GCF_036698935#LFB18_RS00860
LFB18_RS00860 · HK · Classic
RefSeq: WP_021422393.1
GCF_036699115#LFB33_RS16025
LFB33_RS16025 · HK · Classic
RefSeq: WP_021422393.1
GCF_036699395#LFB03_RS00860
LFB03_RS00860 · HK · Classic
RefSeq: WP_021422393.1
GCF_900164115#B2C73_RS04190
B2C73_RS04190 · HK · Classic
RefSeq: WP_021422393.1
GCF_900164195#B2C60_RS03420
B2C60_RS03420 · HK · Classic
RefSeq: WP_021422393.1
GCF_900164965#B2C44_RS01685
B2C44_RS01685 · HK · Classic
RefSeq: WP_021422393.1
GCF_900165315#B2B62_RS03345
B2B62_RS03345 · HK · Classic
RefSeq: WP_021422393.1
GCF_900165435#B2C32_RS03345
B2C32_RS03345 · HK · Classic
RefSeq: WP_021422393.1
GCF_900165835#B2C10_RS02405
B2C10_RS02405 · HK · Classic
RefSeq: WP_021422393.1
GCF_900688565#E1149_RS00910
E1149_RS00910 · HK · Classic
RefSeq: WP_021422393.1
GCF_900691955#E1221_RS02415
E1221_RS02415 · HK · Classic
RefSeq: WP_021422393.1
GCF_901004575#FJF35_RS06100
FJF35_RS06100 · HK · Classic
RefSeq: WP_021422393.1
GCF_901004615#FJF66_RS05080
FJF66_RS05080 · HK · Classic
RefSeq: WP_021422393.1

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001255
AssemblyASM700125v1 · Contighaploid
Genome composition4 498 869 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 50 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key