Gene detail

D1N53_RS05190

Histidine kinase, Classic

Clostridioides difficile · GCF_007001255

ClassHKTypeClassicLength222 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_007001255#D1N53_RS05190Stable P2CS identifier used across views.
GenomeGCF_007001255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557917Run 6 · 52 sequences · id 100% · cov 80%
External referencesWP_142801758.1 · MIST4 D1N53_RS05190RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length222 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage157 / 222 aa (70.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa222 aa
HisKA: 2-53 aa (52 aa)1HATPase_c: 114-218 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
2-53 aa · 52 aa · 23.4% of protein
Raw tokenHisKA:2:0.00000007:53:52:64
2 HATPase_c#2
114-218 aa · 105 aa · 47.3% of protein
Raw tokenHATPase_c:114:8.51e-22:218:106:109
  • Raw architecture: HisKA:2:0.00000007:53:52:64#HATPase_c:114:8.51e-22:218:106:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_007001255::NZ_QWVH01000015.1::G00015
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span57040-57709Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N53_05190RefSeq proteinWP_142801758.1
Context group IDGCF_007001255::NZ_QWVH01000015.1::G00015
Context members
D1N53_RS05190
Partner locus tags
D1N53_RS05190
Partner old locus tags
D1N53_05190
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_142801758.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N53_RS05190Primary locus identifier stored in the genes table.
Old locus tagD1N53_05190Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVH01000015.1Sequence record reported by the local genomic context database.
Genomic interval57 040-57 709 nt670 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span57 040-57 709 ntGCF_007001255::NZ_QWVH01000015.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001255::NZ_QWVH01000015.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVH01000015.1All displayed genes belong to this local TCS context.
Neighborhood span57 040-57 709 nt670 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
57 040 nt57 709 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

D1N53_RS05190GCF_007001255#D1N53_RS05190
HKClassicCurrent focus

57 040-57 709 nt · Reverse (-)

Old locus D1N53_05190RefSeq WP_142801758.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557917Run 6 · HK · 52 sequences
Representative sequenceGCF_000451765#QSM_RS15875Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557917

Simplified PFAM architecture for HKOC_2557917

PFAM domain coverage: 219 / 386 aa (56.7%)

1 aa386 aa
HAMP: 106-151 aaHAMPHisKA: 164-231 aaHisKAHATPase_c: 278-382 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[106-151] | HisKA[164-231] | HATPase_c[278-382]
  • Domain count: 3
  • Matched identifier: HKOC_2557917
  • Positioned domains: HAMP 106-151 ; HisKA 164-231 ; HATPase_c 278-382
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451765#QSM_RS15875

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001255
AssemblyASM700125v1 · Contighaploid
Genome composition4 498 869 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 109 · HK 50 · RR 56CheA 1 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key