Gene detail

D1N54_RS00435

Histidine kinase, Classic

Clostridioides difficile · GCF_007001225

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_007001225#D1N54_RS00435Stable P2CS identifier used across views.
GenomeGCF_007001225Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503595Run 6 · 52 sequences · id 100% · cov 80%
External referencesWP_021422020.1 · MIST4 D1N54_RS00435RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 182-240 aa (59 aa)1HATPase_c: 293-391 aa (99 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000133:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:1.11e-18:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000133:240:59:64#HATPase_c:293:1.11e-18:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_007001225::NZ_QWVG01000001.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span100211-102054Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD1N54_00435RefSeq proteinWP_021422020.1
Context group IDGCF_007001225::NZ_QWVG01000001.1::G00020
Context members
D1N54_RS00430D1N54_RS00435
Partner locus tags
D1N54_RS00430D1N54_RS00435
Partner old locus tags
D1N54_00430D1N54_00435
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021422020.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD1N54_RS00435Primary locus identifier stored in the genes table.
Old locus tagD1N54_00435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_QWVG01000001.1Sequence record reported by the local genomic context database.
Genomic interval100 873-102 054 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span100 211-102 054 ntGCF_007001225::NZ_QWVG01000001.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_007001225::NZ_QWVG01000001.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_QWVG01000001.1All displayed genes belong to this local TCS context.
Neighborhood span100 211-102 054 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
100 211 nt102 054 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D1N54_RS00430GCF_007001225#D1N54_RS00430
RROmpR

100 211-100 873 nt · Forward (+)

Old locus D1N54_00430RefSeq WP_003434705.1
D1N54_RS00435GCF_007001225#D1N54_RS00435
HKClassicCurrent focus

100 873-102 054 nt · Forward (+)

Old locus D1N54_00435RefSeq WP_021422020.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503595Run 6 · HK · 52 sequences
Representative sequenceGCF_000451765#QSM_RS15995Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503595

Simplified PFAM architecture for HKOC_2503595

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503595
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000451765#QSM_RS15995

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_007001225
AssemblyASM700122v1 · Contighaploid
Genome composition4 283 259 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 108 · HK 53 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key